Lipids, lipoproteins, and drugs
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Bibliographic Information
Lipids, lipoproteins, and drugs
（Advances in experimental medicine and biology, v. 63）
Plenum Press, c1975
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Sponsored by Italian Society of Pharmacology, Fondazione Giovanni Lorenzini, Milan, Italy, International Society for Biochemical Pharmacology
Includes bibliographical references and indexes
Description and Table of Contents
Table of Contents
Opening Remarks.- Chemistry and Physiology of Lipoproteins.- The Interaction of Apolipoprotein-Alanine (ApoC-III) with Lipids: Study of Structural Features Required for Binding.- Lipoproteins and Lipid Transport.- Pathways of Lipoprotein Metabolism: Integration of Structure, Function and Metabolism.- Steroid Requirements for Suppression of HMG-CoA Reductase Activity in Cultured Human Fibroblasts.- The Immunology of Serum Lipoproteins.- Biochemical Pharmacology of Hypolipidemic Drugs.- Hormone-Induced Lipolysis and the Metabolic Pathways Providing Energy to the Cell: A Possible Role of ATP as a Rate-Limiting Factor.- Mechanism of Action of Hypolipidemic Drugs.- Newer Hypolipidemic Compounds.- Experimental and Clinical Evaluation of Two "Atromid-S" Analogues in Relation to Their Differential Modes of Action.- Approaches to Treatment of Hyperlipidemias.- Pathogenesis of Hyperlipidemias, Clues to Treatment?.- Serum Lipoprotein Composition in Different Types of Hyperlipoproteinemia.- Diet in the Management of Hyperlipidemic Patients.- The Partial Ileal Bypass Operation in Treatment of the Hyperlipidemias.- Drugs and Thrombosis.- The Activation and Inhibition of Fibrinolysis.- The Role of Lipids in the Tissue Factor Pathway of Blood Coagulation.- Use of Fibrinopeptide A Measurements in the Diagnosis and Management of Thrombosis.- Modifications of Platelet Functions by Dietary Fats.- Risk Factors Other than Diet.- Diabetes as a Risk Factor for Arteriosclerotic Vascular Disease.- Hypertension and Other Risk Factors.- The Heritable Hyperlipoproteinemias and Atherosclerosis.- Smoking and Carbon Monoxide Uptake as a Risk Factor in Atherosclerotic Cardiovascular Disease.- Risk of Coronary Disease and Coronary Complications by Neural and Psychological Factors.- Animal Models for Atherosclerosis Research.- New Animal Model for Atherosclerosis Research.- Effects of Various Hypolipidemic Drugs on Fatty Acid Composition of Liver and Serum Lipids.- Some Aspects of the Chimpanzee as a Model for Experimental Atherosclerosis.- Studies on Experimental Atherosclerosis by Immunofluorescence.- The Effects of Tolbutamide on the Development of Atherosclerosis in Rhesus Monkeys Fed an Average American Table-Prepared Diet.- The Cockerel as an Animal Model for Atherosclerosis Research.- Influence of Platelets on the Integrity of the Vessel Wall.- Scope and Organization of a Lipid Clinic and Clinical Trials.- Scope and Organization of a Lipid Clinic and Clinical Trials.- Portacaval Shunt in Two Patients with Homozygous Hypercholesterolemia.- Planning the Type II Coronary Primary Prevention Trial of the Lipid Research Clinics (U. S. A.).- Concluding Remarks.- Abstracts of Submitted Papers.- Author Index.
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