L-Carnitine and its role in medicine: from function to therapy
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書誌事項
L-Carnitine and its role in medicine: from function to therapy
Academic Press, c1992
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内容説明・目次
内容説明
During the past decade, it has become increasingly evident that L-carnitine is intimately involved in many different aspects of medicine. The precise nature of this involvement is the subject of ongoing studies being conducted in clinics and laboratories world wide. The purpose of this book is to provide an introductory overview of the metabolism of carnitine and its role in medicine as it is understood today. Any advances in our understanding to be made in the future might then be better placed in context.
The first comprehensive review of the function and therapeutic uses of L-carnitine, the book includes three sections covering a general introduction to the basic aspects of carnitine metabolism, and the involvement of carnitine in the clinical aspects of pediatric medicine and of adult medicine.
目次
Introduction to L-Carnitine:
S. Di Mauro, Role of Carnitine, An Overview.
C. Hoppel, The Physiological Role of Carnitine.
E. Brass, Carnitine Transport.
F. Di Lisa, L.L. Bieber, and N. Siliprandi, Methods for Carnitine Assay.
V. Rizza, R. Lorefice, N. Rizza, and V. Calabrese, Pharmacokinetics of L-Carnitine in Human Subjects.
S. DiDonato, B. Garavaglia, M. Rimoldi, and F. Carrara, Introduction to Clinical and Biomedical Aspects of Carnitine Deficiencies.
Pediatric Medicine:
G. Sherwood, Carnitine and Pediatrics: An Overview.
M. Novak, Carnitine in Perinatal Metabolism of
Lipids.
E. Schmidt-Sommerfeld and D. Penn, Role of Carnitine in Children Receiving Total Parenteral Nutrition.
C. Angelini, A. Martinuzzi, and L. Vergani, Treatment with L-Carnitine of the Infantile and Adult Form of Primary Carnitine Deficiency.
I. Tein and S. DiMauro, Primary Systemic Carnitine Deficiency Manifested by Carnitine-Responsive Cardiomyopathy.
M.J. Bennet and D.E. Hale, Defects of Mitochondrial ~gb-Ocidation Enzymes.
S. Winter, W.H. Vance, E.M. Zorn, C.K. Vance, K. Jue, G. Opala, L. Linn, A.B. Burlina, G.M. Gagliardi, G. Sabetta, and E. Bertini, Carnitine Deficiency in Pediatrics: Experience at Valley Children's Hospital, Fresno, California.
Adult Medicine:
R. Ferrari, Carnitine in Adults: An Overview.
O. Visioli, E. Pasini, F. de Giuli, and R. Ferrari, Molecular
Mechanism of Action of L-Carnitine in Treatment of Myocardial Ischaedia and Reperfusion.
R. Ferrari and O. Visioli, Effects of L-Carnitine in Coronary Artery Disease Patients.
P. Rizzon, M. Di Biase, and G. Biasco, Treatment of Acute Myocardial Infarction with L-Carnitine.
V. Regitz and E. Fleck, Role of Carnitine in Heart Failure.
A.K. Patel, J.H. Thompson, P.K. Kosolcharoen and A.L. Shug, Myocardial Carnitine Status: Clinical, Prognostic, and Therapeutic Significance.
C. Fernandez, Profile of the Safety of Long-Term L-Carnitine Therapy in Cardiopathic Patients.
W.C. H~adulsman and N. Dubelaar, Carnitine in Metabolism of Paced Cardiac and Skeletal Muscles: Prevention of Acidosis and Improvement of Vascular Flow.
C. Brevetti and S. Perna, Metabolic and Clinical Effects of L-Carnitine in Peripheral Vascular Disease.
S. Ahmad, Carnitine, Kidney, and Renal Dialysis.
G.D. Lopaschuk, Effects of Carnitine and Carnitine Acyltransferase Inhibition on Energy Substrate Utilization in the Intact Heart.
N.S. Dhalla, I.M.C. Dixon, K.R. Shah and R. Ferrari, Beneficial Effects of L-Carnitine and Derviatives on Heart Membrane in Experimental Diabetes.
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