The Blood-brain barrier : cellular and molecular biology
著者
書誌事項
The Blood-brain barrier : cellular and molecular biology
Raven Press, c1993
- タイトル別名
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Blood brain barrier
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This volume focuses on the cellular and molecular biology of the blood-brain barrier (BBB), a membrane that, until recently, was studied only from the perspective of whole-organ physiology. The book presents concepts and experimental methods that are of vital importance to neuroscientsts, cellular and molecular biologists, pharmacologists developing strategies for drug delivery to the brain, and immunologists studying lymphocyte trafficking and antigen presentation at the blood-brain barrier. Sections of the book cover cell-cell interactions; brain capillary-specific genes. The contributors' reviews of recent research in these areas provide crucial insights into how the cells of the BBB acquire their specialized biochemical properties, and how these cells transport nutrients, peptides, proteins, and immune cells from circulating blood to the brain.
目次
- Part 1 Cell-cell interactions: brain microvessels and microvascular cells in vitro, John Laterra and Gary W. Goldstein
- brain endothelial-astrocyte interactions, P.A. Cancilla, et al
- antigen presentation at the cerebral microvasculature, Zsusanna Fabry and Michael N. Hart
- lymphocyte traffic to the brain, Hartmut Wekerle
- cell-cell adhesion molecules of the blood-brain barrier, Ronald L. Heimark. Part 2 Subcellular organelle function: tight junctions of brain endothelium and epithelium, M.W. Brightman and J.H. Tao-cheng
- microvascular pericytes in development and disease, Ira M. Herman
- morphological evidence of the functional polarization of brain microvascular endothelium, Andrzej W. Vorbrodt
- a cell biological perspective for the transcytosis of peptides and proteins through the mammalian blood-brain fluid barriers, Richard D. Broadwell and William A. Banks
- lysosomes of brain and other vascular endothelia, Kenneth L. Audus and Thomas J. Raub. Part 3 Signal transcution mechanisms: receptor-mediated transport of peptides and proteins across the blood-brain barrier, Phillip M. Friden
- brain microvascular vasoactive agents - receptors and mechanisms of action, Christian Frelin and Paul Vigne
- brain microvascular cyclic nucleotides and protein phosphorylation, Ferenc Joo
- phosphoinositide turnover in the brain microvasculature, Lester R. Drewes
- oxygen free radicals and the brain microvasculature, A. Lorris Betz. Part 4 Gene expression: subtraction cloning of genes selectively expressed at the blood-brain barrier, Hartmut Weiler-Guettler, et al
- gamma-glutamyl transpeptidase - molecular cloning and structural and functional features of a blood-brain barrier market protein, Andreas Frey
- molecular cloning of a blood-brain barrier cell surface glycoprotein, Harald Seulberger and Werner Risau
- molecular cloning and regulation of gene expression of glood-brain barrier glucose transporter, William M. Pardridge and Ruben J. Boado
- molecular cloning of choroid plexus-specific transport proteins, Gerhard Schreiber, et al.
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