Steroid hormone action
著者
書誌事項
Steroid hormone action
（Frontiers in molecular biology）
IRL Press, c1993
- : hbk
- : pbk
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注記
Includes bibliographical references and index
内容説明・目次
- 巻冊次
-
: pbk ISBN 9780199633920
内容説明
Steroid Hormone Action is a comprehensive overview of the molecular mechanisms by which these hormones regulate the expression of specific target genes. The book covers the structure of steroid receptors, transcriptional activation and repression, and also contains chapters on steroid binding proteins and steroidogenesis. Steroid receptors represent one of the best characterized transcription factors so that the book will be of general interest to
Molecular Biologists studying eucaryotic gene regulation. Chapters on the mechanisms of action of steoid antagonists and defective receptors in target cells will be of particular interest to Endocrinologists and Clinicians. In such a rapidly progressing field it is difficult to keep up with all the literature but
this book, written by international experts, focuses on the most important advances that have been made recently.
目次
- 1. Extracellular steroid-binding proteins
- 2. Importance of steroidogenesis in specific hormone action
- 3. Overview of the steroid receptor superfamily of gene regulatory proteins
- 4. Role of heat-shock proteins in steroid receptor function
- 5. Nuclear hromone receptors as transcriptional activators
- 6. Repression of transcription by nuclear receptors
- 7. Structure and function of the steroid receptor zinc finger region
- 8. Mechanism of action of hormone antagonists
- 9. Mutations in steroid hormone receptors causing clinical disease
- Index
- 巻冊次
-
: hbk ISBN 9780199633937
内容説明
This volume provides a detailed overview of the mechanisms by which steroid hormones regulate gene activity in target cells. The book covers the structure of steroid receptors, transcriptional activation and repression, and also contains chapters on steroid binding proteins and steroidgenisis. Steroid receptors represent one of the best characterized transcription factors so that the book will be of interest to molecular biologists studying eucaryotic gene regulation. Chapters on the mechanisms of action of steroid antagonists and defective receptors in target cells will be of particular interest to endocrinologists and clinicians.
目次
- Extracellular steroid-binding proteins
- Importance of steroidogenesis in specific hormone action
- Overview of the steroid receptor superfamily of gene regulatory proteins
- Role of heat-shock proteins in steroid receptor function
- Nuclear hormone receptors as transcriptional activators
- Repression of transcription by nuclear receptors
- Structure and function of the steroid receptor zinc finger region
- Mechanism of action of hormone antagonists
- Mutations in steroid hormone receptors causing clinical disease.
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