Recent progress in atherosclerosis research
著者
書誌事項
Recent progress in atherosclerosis research
（Current topics in pathology, 87）
Springer-Verlag, c1993
- : gw
- : us
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This monograph on recent progress in atherosclerosis research presents state-of-the art morphological investigations on the cells and their metabolism in the atherosclerotic plaque in situ. The spectrum of methods includes immunohistologic and immunoelectron microscopic investigations on the localization of apolipoproteins in the cells of the arterial intima, presenting new data on the lipoprotein metabolism in plaque. The collagen metabolism is analyzed by in situ hybridization techniques for demonstrating the synthesis of different collagen types on the messenger RNA level. Concentrating on in situ investigations with sophisticated morphological methods, the discussion in this volume on atherogenesis is focused on the arterial wall and its morphological alterations. As morphology remains the basis for understanding the pathogenesis of disease, the results presented here should be of interest not only to pathologists, but also to clinicians and researchers working in the field of the biology of atherosclerosis.
目次
Pathobiochemical Changes of the Arterial Wall at the Inception of Atherosclerosis.- Angiogenic Processes in the Pathogenesis of Human Coronary Atherosclerosis.- Differentiation and Role of Macrophages in the Early Human Atherosclerotic Plaque.- Lipoprotein Receptors on Macrophages and Smooth Muscle Cells.- In Situ Localization and Distribution Pattern of Apolipoproteins in Arterial Walls: A Comparative Study in Atherosclerosis and Renal Transplant Arteriopathy.- Collagens in Atherosclerotic Vessel Wall Lesions.- Metabolism of Fibromuscular and Atheromatous Plaques in an Experimental Model: Causal Mechanisms for the Development of Intimal Necrosis.- Parallels Between Renal Transplant Arteriopathy and Atherosclerosis in Respect of Functional Morphology.
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