Quantitative cancer modeling and risk assessment

書誌事項

Quantitative cancer modeling and risk assessment

Charles D. Holland, Robert L. Sielken, Jr.

Prentice Hall, c1993

大学図書館所蔵 件 / 2

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This volume covers widely-used classical models for cancer formation, virtually safe doses, recent advances in the modelling and analysis of dose-response experiment, and a weight-of-evidence approach to quantitative cancer-risk assessment.

目次

  • A review of the science of cancer formation
  • development of selected classical models for cancer formation
  • quantifying virtual safe doses and risk assessment
  • concepts used in the statistical analysis of animal tests
  • incorporating cell-proliferation- and physiological-based pharmacokinetics (PHPK) into dose-response models
  • biologically-based dose scales for dose-response modeling
  • a weight of evidence approach to quantitative cancer risk assessement.

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