Cancer chemotherapy : challenges for the future : proceedings of the Eighth Nagoya International Symposium on Cancer Treatment, Nagoya, Japan, October 16-17, 1992
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Bibliographic Information
Cancer chemotherapy : challenges for the future : proceedings of the Eighth Nagoya International Symposium on Cancer Treatment, Nagoya, Japan, October 16-17, 1992
（International congress series, no. 1048）
Excerpta Medica, 1993
- v. 8
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Note
Includes bibliographies and index
Description and Table of Contents
Description
The theme of the symposium on which this book is based was "New therapeutic concepts and their clinical applications", in which the keynote address discusses recent progress in and future prospects for the treatment of aggressive lymphomas. The section on new therapies and concepts suggests that further studies at the level of genes and chromosomes are necessary for future progress in cancer chemotherapy. Presentations on the mechanism of leukemogenesis focusing on gene rearrangements indicates that in the near future gene therapy will be available for the treatment of leukemia and lymphoma. New differentiation inducers with reference to glycobiology and all-trans retinoic acid therapy in the treatment or' acute promyelocytic leukemia is reviewed, as is cure-oriented intensive chemotherapy, acute leukemia, malignant lymphoma, and the new drug taxol. This book will provide new therapeutic concepts to many oncologists, especially cancer chemotherapists, working in both basic and clinical research.
Table of Contents
- Preface. Keynote Address. Treatment of aggressive lymphomas: Recent progress and future prospects (D.L. Longo). New Therapies and Concepts. Inhibition of Philadelphia' leukemia cell growth by bcr-abl antisense oligodeoxynucleotides. (B. Calabretta et al). Azatyrosine: A potential anti-carcinogenic and anti-cancer agent that induces permanent conversion of mouse and human ras-transformed cells to apparendy normal phenotype (S. Nishimura et al). Immunotherapy and gene therapy for human cancer using T-lymphocytes (y Kawakami et al.). Cytokine gene delivery for immunotherapy of cancer (Y Kohgo et at). Special Lecture. RBTN and HOXII genes: Paradigms of translocation junction genes in childhood T cell acute leukaemia (T.H. Rabbitts et al). Mechanism of Leukemogenesis Focusing on Gene Rearrangements. Functional properties of chimeric transcription factors in acute leukemias (M.L. Cleary). Involvement of BCL3 gene in chronic lymphocytic leukemia (H. Ohno et al). Translocation-associated genes on chromosome 11 in B-cell malignancy (M. Seto). Analysis of I lq23 chromosome translocation breakpoints aqssociated with human leukemia (M.O. Diaz, et al Analysis of I I q23 breakpoints in leukemia by fluorescent in situ hybridization with I lq23-specific cosmid markers (J. Inazawa, T. Abe). The t(8
- 2 1) translocation in acute myeloid leukemia results in production of an AMLI-MTG8 fusion transcript (H. Miyashi et al). Transgenic models of leukaemogenesis (J.M. Adams et al.). Differentiation Therapy and Retinoids. New differentiation inducers with reference to glycobiology: Bioactive. glycolipids and mechanism(s) f their action (M. Saito). PML-RAR, a fusion protein in human acute promyelocytic leukemia (A. Kakizuka et al). ATRA -therapy in acute promyelocytic leukimia :from clinical results to molecular biology (L. Degos).- Treatment of acute promyclocytic leukemia with all-trans retinoic acid and molecular analysis of the t(I 5
- 17) translocation (T Name et al.). Retinoids (K. Shudo et al.). Cure-oriented Intensive Chemotherapy of Hematological Malignancies. Multiple Myeloma. Chemotherapy and prognosis of multiple myeloma (R.A. Kyle). Chemotherapy plus interferon-alpha in the treatment of multiple myeloma: A cooperative study (H. Mizoguchi et al). Disappearance of M-protein in the treatment of multiple myeloma (T. Adachi et al.). Acute Leukemia. Intensive chemotherapy of adult acute myeloid leukemia and acute lymphoblastic leukemia (Th. Buchner). Japan Adult Leukemia Study Group (JALSG) AML-87 study of I acute myeloid leukemia in adults (M. Tanimoto et al.). 'Analysis of long-term survivors of acute leukemia in adults (E. Nagura et al). Preganacy and delivery among long-term survivors of adult acute leukemia -a nationwide study (S. Kawamura et al). What is the optimal strategy to prevent relapse in children with acute myeloid leukemia? (S.A. Feig et al). Treatment strategy for children with acute lymphoblastic
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