CiNii 図書 - Genes V

This is the latest edition of the core text for courses in molecular biology, genetics, cell biology, and related disciplines. "Genes V" provides more introductory material than earlier editions. The contents have been thoroughly revised, reflecting new knowledge and advances. A new section on cell biology integrates material scattered throughout previous editions with the latest developments. The whole book has a greater coherence and more logical structure than ever before. This is reflected by a design which should help to illustrate major points and summarize large amounts of work. People who should find this book interesting include undergraduates in the second, third or fourth years (and sometimes even the first year) of a degree course in molecular biology, biochemistry, genetics, microbiology, virology, cell biology, or preclinical medicine. Research students and scientists who need a thoroughly up-to-date, well-integrated, and authoritative account of the science which may not be their original discipline but has a major impact on their work and that of their competitors should also find this book of interest.

Cells as macromolecular assemblies
Cells obey the laws of physics and chemistry
Cells are organized into compartments. Part 1 DNA as a store of information: Genes are mutable units
DNA is the genetic material
The topology of nucleic acids
Isolating the gene. Part 2 Translation: expressing genes as proteins
The assembly line for protein synthesis
Transfer RNA is the translational adaptor
Ribosomes provide a translation factory
Messenger RNA is the template. Part 3 Constructing the cell: The apparatus for protein localization
Receptors and signal transduction: channels and ion uptake
Cell cycle and growth regulation. Part 4 Control of prokaryotic gene expression: Control at initiation: RNA polymerase-promoter interactions
A panoply of operons - the lactose paradigm and others
Control by RNA structure - termination and antitermination
Phage strategies - lytic cascades and lysogenic repression. Part 5 Perpetuation of DNA: The replicon - unit of replication
Primosomes and replisomes - the apparatus for DNA replication
Systems that safeguard DNA. Part 6 Organization of the eukaryotic genome: The extraordinary power of DNA technology
Genome size and genetic content
The eukaryotic gene - conserved exons and unique introns
Gene numbers - repetition and redundancy
Genomes sequestered in organelles
Organization of simple sequence DNA
The genome is packaged into chromosomes
Chromosomes consist of nucleosomes. Part 7 Eukaryotic transcription and RNA processing: Building the transcription complex - promoters, factors, and RNA polymerases
Regulation of transcription - factors that activate the basal apparatus
The apparatus for nuclear splicing
RNA as catalyst - changing the informational content of RNA. Part 8 The dynamic genome: DNA in flux
Recombination of DNA
Transposons that mobilize via DNA
Retroviruses and retroposons
Rearrangement and amplification in the genome. Part 9 Genes in development
Generation of immune diversity by gene reorganization
Gene regulation in development - gradients and cascades
Oncogenes - gene expression and cancer
Epilogue.

巻冊次: : pbk ISBN 9780198542889

内容説明

This is the latest edition of the core text for courses in molecular biology, genetics, cell biology, and related disciplines. "Genes V" provides more introductory material than earlier editions. The contents have been thoroughly revised, reflecting new knowledge and advances. A brand new section on cell biology integrates material scattered throughout previous editions with the latest developments. The whole bookhas a greater coherence and more logical structure than ever before. This is reflected by a design which should help to illustrate major points and summarize large amounts of work. People who should find this book interesting include undergraduates in the second, third or fourth years (and sometimes even the first year) of a degree course in molecular biology, biochemistry, genetics, microbiology, virology, cell biology, or preclinical medicine. Research students and scientists who need a thoroughly up-to-date, well-integrated, and authoritative account of the science which may not be their original discipline but has a major impact on their work and that of their competitors should also find this book of interest.

Cells as macromolecular assemblies
Cells obey the laws of physics and chemistry
Cells are organized into compartments. Part 1 DNA as a store of information: Genes are mutable units
DNA is the genetic material
The topology of nucleic acids
Isolating the gene. Part 2 Translation: expressing genes as proteins
The assembly line for protein synthesis
Transfer RNA is the translational adaptor
Ribosomes provide a translation factory
Messenger RNA is the template. Part 3 Constructing the cell: The apparatus for protein localization
Receptors and signal transduction: channels and ion uptake
Cell cycle and growth regulation. Part 4 Control of prokaryotic gene expression: Control at initiation: RNA polymerase-promoter interactions
A panoply of operons - the lactose paradigm and others
Control by RNA structure - termination and antitermination
Phage strategies - lytic cascades and lysogenic repression. Part 5 Perpetuation of DNA: The replicon - unit of replication
Primosomes and replisomes - the apparatus for DNA replication
Systems that safeguard DNA. Part 6 Organization of the eukaryotic genome: The extraordinary power of DNA technology
Genome size and genetic content
The eukaryotic gene - conserved exons and unique introns
Gene numbers - repetition and redundancy
Genomes sequestered in organelles
Organization of simple sequence DNA
The genome is packaged into chromosomes
Chromosomes consist of nucleosomes. Part 7 Eukaryotic transcription and RNA processing: Building the transcription complex - promoters, factors, and RNA polymerases
Regulation of transcription - factors that activate the basal apparatus
The apparatus for nuclear splicing
RNA as catalyst - changing the informational content of RNA. Part 8 The dynamic genome: DNA in flux
Recombination of DNA
Transposons that mobilize via DNA
Retroviruses and retroposons
Rearrangement and amplification in the genome. Part 9 Genes in development
Generation of immune diversity by gene reorganization
Gene regulation in development - gradients and cascades
Oncogenes - gene expression and cancer
Epilogue.

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Genes V

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