Biology of vitronectins and their receptors : proceedings of the First International Vitronectin Workshop, Rauischholzhausen Castle, Marburg, Germany, 25-28 August, 1993
著者
書誌事項
Biology of vitronectins and their receptors : proceedings of the First International Vitronectin Workshop, Rauischholzhausen Castle, Marburg, Germany, 25-28 August, 1993
（International congress series, no. 1042）
Excerpta Medica, 1993
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注記
Includes bibliographical references, and author & keyword indexes ( p. 361-367)
内容説明・目次
内容説明
This volume brings together the work of scientists from different fields of biological/biomedical research whose activities concentrate on cellular adhesion related to a variety of physiological and pathophysiological conditions. In this respect, the common players among diverse biological systems are the multifunctional adhesive protein, vitronectin and . related components; several chapters are devoted to the role of vitronectin receptors in relation to different physiological settings. This volume will be of great value to haematologists, cell biologists, clinical biochemists and immunologists, and molecular biologists.
目次
Part 1 Vitronectin Structure, Biosynthesis, Processing and Distribution: Vitronectins: From vertebrates to invertebrates (M. Hayashi). Purification of stabilised native vitronectin (I. Hayashi, D.F Mosher). Multimeric vitronectin: Structure and function (S. Hess et al). Vitronectin-integrin interactions: Analysis by site-directed mutations (R.C. Cherny, P. Thiagarajan). A comparison of vitronectin and megakaryocyte stimulating factor (D.M. Merberg et al). Binding domain P-endorphin and vitronectin (S. Wohner et al). Primary structure of vitronectins and homology with other proteins (H.J. Ehrlich et al). Distribution of vitronection (R. Seiffert, T.J. Podor, D.J. Loskutoff). Vitronectin expression in human germ cell tumours and normal mouse development (S. Cooper et al). Vitronectin association with skin (K. Dahlback). The distribution of vitronectin in resting and thrombin stimulated platelets. An ultra-immunocytochemical study (E. Morgenstern, K.T. Preissner). Metabolism of vitronectin complexes (H.C. de Boer, Ph. de Groot, K.T. Preissner). Receptor mediated endocytosis of vitronectin by fibroblast monolayers (P.J. McKeown-Longo, T.S. Panetti). Part 2 Vitronectin Receptors and Adhesive Interactions: Platelets, extracellular matrix and integrins (J.J. Sixma, H.K. Nieuwenhuis, Ph.G. de Groot). Megakaryocyte specific expression of the allb integrin (G. Marguerie, G. Uzan). Vitronectin receptors in melanoma tumour growth and metastasis (B. Felding-Habermann et al). Peptide and non-peptide antagonists of 0 3 integrins (B. Steiner, W.C. Kouns, T. Weller). Tyrosine phosphorylation of a 38 kDa protein upon interaction of urokinase-type plasminogen activator (u-PA) with its cellular receptor (I. Dumler, T Petri, W.-D. Schleuning). Part 3 Extracellular Matrix Interactions and Alterations: Drosophila development and cellular adhesion (J.H. Fessler et al). Episialin modulate cell-cell adhesion, promotes invasion in matrigel and inhibits cytolysis by cytotoxic effector cells (J. Hilkens et al.). Molecular organisation and antiproliferative activity of arterial tissue heparan sulfate proteoglycans (E. Buddecke et al). Thrombin interaction with the vascular system (R. Bar-Shavit et al.). Vitronectin in inflammatory conditions: Localisation in rheumatoid arthritic synovia (B.R. Tomasini-Johansson). Tenascin and DSD-Iproteoglycan: Extracellular matrix components involved in neural pattern formation and remodelling (A. Faissner et al). Part 4 Immune Defense and Micro-Organisms. Lymphocyte medicated cytotoxicity (E.R. Podack). Structure and function of CD59 (P.J. Sims). (Part contents).
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