Modulation of differentiation by exogenous agents
Author(s)
Bibliographic Information
Modulation of differentiation by exogenous agents
(Mechanisms of differentiation, v. 2)
CRC Press, c1990
- Other Title
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Mechanisms of differentiation
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
Significant recent advances in cell culture technology now permit a detailed biochemical and molecular analysis of differentiation in both normal and tumor cells. These studies are important in attempting to understand the complex factors involved in normal growth and development, as well as the abnormalities associated with carcinogenesis.
Mechanisms of Differentiation, Volumes I and II, is comprised of review chapters addressing various topics of current interest in this important area of research. Topics discussed include genes controlling differentiation, changes in gene expression during differentiation, induction of differentiation, induction of differentiation as a mode of action of chemotherapeutic agents, and the effect of cell shape, growth factors and differentiation modulating agents on the differentiated cell phenotype.
Mechanisms of Differentiation is valuable to researchers involved in differentiation and development, carcinogenesis, cell biology, chemotherapy, and immunology.
Table of Contents
VOLUME II: MODULATION of DIFFERENTIATION by EXOGENOUS AGENTS
Modulation of Differentiation: Potential Mechanism by Which Inferferons Induce Antitumor Activity
Regulation of Tumor Antigen Expression by Recombinant Interferons
Induction of Terminal Differentiation of Human Leukemic Cells by Chemotherapeutic and Cytotoxic Drugs
Induced Differentiation of Transformed Cells with Polar/Apolar Compounds and the Reversibility of the Transformed Phenotype
5-Azacytidine
Induction of Differentiation in Fibroblast Cells by Irradiation and Chemical Carcinogens
The Early Reactions and Factors Involved in In Vitro Erythroid Differentiation of Mouse Erythroleukemia (MEL) Cells
Regulation of Cell Contacts, Cell Configuration and Cytoskeletal Gene Expression in Differentiating Systems
Macrophage and Granulocyte Macrophage-Colony Stimulating Factor Effects on Human Monocyte Differentiation
Regulation of Phenotype by Transforming Growth Factor-b: Role of the Extracellular Matrix
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