Resealed erythrocytes as carriers and bioreactors : proceedings of the Third International Meeting held at the Gwinn Estate, Cleveland, Ohio, USA, 18-20 October, 1989
著者
書誌事項
Resealed erythrocytes as carriers and bioreactors : proceedings of the Third International Meeting held at the Gwinn Estate, Cleveland, Ohio, USA, 18-20 October, 1989
（Advances in the biosciences, v. 81）
Pergamon Press, c1991
1st ed
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Recent years have seen an improved understanding of the biology of the red cell and its bounding membrane. At the same time there have been technical improvements in procedures for preparing resealed erythrocytes and new ideas for using them as carriers for drugs and as cellular bioreactors. This third international meeting on the application of resealed erythrocytes was the first in the series to be held in North America. The sessions covered the methodology of preparing resealed erythrocytes and properties of model systems, the evaluation of these carriers for delivery of immunomodulators and anti-neoplastic drugs. Several contributions also considered the potential chemical application of these techniques in human and veterinary medicine. This volume will be of interest to pharmacologists and those interested in the clinical application of this promising biotechnology.
目次
- Selected papers. Temperature effect on the rightward shift of the oxyhemoglobin dissociation curve in physiological conditions, Ch Bailleul et al . Human and murine erythrocytes as bioreactors releasing the antineoplastic drug 5-fluoro-2'-deoxyuridine, E Zocchi et al . An SEM study of morphological changes in erythrocytes from several species during carrier cell preparation, R E Droleskey el al . Aprotinin release by loaded mouse erythrocytes, G Falcioni et al . Low affinity RBC prepared by the osmotic pulse method: analysis of heterogeneity by density fractionation and flow cytometry, R S Franco et al . Erythrocyte carriers made osmotically and by electroporation: evidence for uptake by endocytosis as well as by passive diffusion, C A Kruse & G W Miera
- . Increased glucose consumption by human and mice erythrocytes overloaded with hexokinase and glucose oxidase, L Rossi et al . Viability of the IHP-loaded red cell in the hypoperfused isolated rat heart, M Samaja et al . The large scale production of white ghosts by hypoosmotic dialysis and ultrafiltration, C L Sheffield & J R DeLoa
- h. Opportunities and pitfalls in the potential use of resealed erythrocytes with incorporated xenobiotics, M Weiner. Enhanced antineoplastic efficiency of erythrocyte encapsulated doxorubicin in a murine liver metastatic model, E Zocchi et al . Electroporation of human recombinant intereukin-2 and its encapsulation into erythrocyte carriers: demonstration of its bioactivity, D H Mitchell et al . Subject index.
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