HIV, AIDS, and the brain

著者

書誌事項

HIV, AIDS, and the brain

editors, Richard W. Price, Samuel W. Perry

(Research publications / Association for Research in Nervous and Mental Disease, v. 72)

Raven Press, c1994

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注記

Papers from the 72nd Annual ARNMD Meeting held in New York in Dec. 1992

Includes bibliographical references and index

内容説明・目次

内容説明

This volume presents reviews of the pathogenesis and clinical aspects of the AIDS dementia complex (ADC), a neurological disorder directly caused by HIV-1. The opening section examines the principal forces involved in the viral pathogenesis of ADC, ie HIV-1 neurotropism, immune system interactions with viruses, and cytokine circuits in the brain. An extensive section on the neuropathology and pathogenesis of ADC includes studies on the role of macrophages and microglia, the cellular neuropathology of HIV encephalitis, and the role of cytokines and amino acids excitotoxicity in mediating neuronal injury. The concluding section focuses on clinical features, evaluation and management of HIV-related psychiatric disorders, ADC and pediatric HIV encephalopathy.

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  • Research publications

    Association for Research in Nervous and Mental Disease

    Raven Press , Williams and Wilkins

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