Antimicrobial agents and intracellular pathogens

書誌事項

Antimicrobial agents and intracellular pathogens

edited by Didier Raoult

CRC Press, c1993

大学図書館所蔵 件 / 3

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Antimicrobial Agents and Intracellular Pathogens is the first book devoted to the relationships among intracellular pathogens, antibiotics, and cells. The book is divided into two sections. Part One describes the effects of antibiotics on uninfected and infected phagocytic cells, the subcellular location of antibiotic compounds, the subcellular compartment of intracellular microorganisms multiplication, and the vectorization of antibiotics. Part Two focuses on intracellular pathogens used as paradigms, including strict intracellular bacteria and antibiotics such as Chlamydia, Rickettsia, Ehrlichia, and Coxiella burnetii; facultative intracellular bacteria and antibiotics such as Legionella and Mycobacteria; and intracellular protozoa and antimicrobial agents, such as Leishmania, Trypnonosoma, and Toxoplasma. This book will be an important reference for microbiologists, clinical microbiologists, infectious disease experts, and researchers in pharmaceutical companies involved in antibiotic development.

目次

Antibiotics and Phagocytic Cells (P.J. van den Broek). Antibiotic Penetration within Eukaryotic Cells (M. Maurin and D. Raoult). Intracellular Location of Microorganisms (D. Raoult and P. Brouqui). Colloidal Carriers of Antibiotics as an Alternative Approach for the Treatment of Intracellular Infections (E. Fattal, O. Balland, H. Alphandary, S. Pecquet, F. Puisieux, P. Couvreur, and A. Andremont). Methodology of Antibiotics Testing for Intracellular Pathogens (M. Drancourt and D. Raoult). Effect of Antimicrobial Agents on Polymorphonuclear Neutrophil Functions (M.T. Labro). Strict Intracellular Bacteria. Antimicrobial Therapy of Rickettsial Spotted Fever (M. Drancourt and D. Raoult). Current Concepts and Perspectives in Q Fever Treatment (M. Maurin and D. Raoult). Susceptibilities of Ehrlichiae to Antibiotics (P. Brouqui and D. Raoult). Chlamydiae (J.M. Ehret and F.N. Judson). Facultative Intracellular Bacteria: Legionella: With Special Emphasis on Antimicrobial Susceptibility Testing (P.H. Edelstein). Mycobacteria as Intracellular Pathogens: Current Notions of Pathogenicity, Virulence, and Drug Resistance and Their Relation to Effective Therapy (N. Rastogi). Intracellular Parasites. Leishmaniasis (J.D. Berman). Trypanosoma cruzi: Considerations of Its Molecular Biology and Biochemistry and Their Applications to Chemotherapy (J.J. Marr). Chemotherapy of Toxoplasma gondii Infections (H.R. Chang and J.-C. Pechere).

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