Microspheres and regional cancer therapy
著者
書誌事項
Microspheres and regional cancer therapy
CRC Press, c1994
大学図書館所蔵 全2件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Microspheres and Regional Cancer Therapy takes an interdisciplinary approach to the subject of microspheres and regional cancer therapy. It synthesizes laboratory and clinical data to demonstrate the utility of microsphere-based strategies in the treatment of localized solid tumors (particularly in the liver) not amenable to surgery and as a component of strategies for treatment of disseminated disease. Using the same techniques that show the deficiencies of delivery strategies involving antibodies, liposomes, and synthetic polymers, clear evidence is presented describing how microspheres of appropriate size can be localized in solid tumor deposits in the liver with little exposure to other organs. To exploit this phenomenon, the extent and nature of the incorporation of active agents within microspheres is discussed in relation to release, pharmacokinetics, and tumor response achieved by intensification of therapy in the manner described. This book will benefit laboratory-based scientists and clinicians in pharmaceutics, pharmacology, physiology, surgical oncology, and nuclear medicine. In addition, cancer clinicians interested in the value of regional therapy will be able to evaluate the underlying theory and learn the necessary methodology.
目次
Chapter 1 -- Pharmaceutical and Methodological Aspects of Microparticles /Yan Chen, Mark A. Burton, and Bruce N. Gray -- Chapter 2 -- Blood Flow and its Modulation in Malignant Tumors /David G. Hirst -- Chapter 3 -- Microparticulate Carriers as a Therapeutic Option in Regional Cancer Therapy: Clinical Considerations /J. H. Anderson, C. S. McArdle, and T. G. Cooke -- Chapter 4 -- Magnetically Controlled Targeted Chemotherapy /P. K. Gupta and C. T. Hung -- Chapter 5 -- Agents for Microsphere Incorporation: Physicochemical Considerations and Physiological Consequences of Particle Embolization /Neville Willmott -- Chapter 6 -- Drug Analysis of Protein Microspheres: From Pharmaceutical Preparation to In Vivo Fate /Jeffrey Cummings, David Watson, and John F. Smyth -- Chapter 7 -- Regional Therapy of Liver Metastases: A Surgeon's View /H. J. Gallagher and J. M. Daly -- Chapter 8 -- Evaluation of the Potential of Microspherical Systems for Regional Therapy in the Tumor-Bearing Liver and Kidney Using Techniques in Nuclear Medicine /Jacqueline A. Goldberg, James H. McKillop, and Colin S. McArdle -- Chapter 9 -- Perspective on Microspheres in Regional Cancer Therapy /Neville Willmott, Bruce Gray, and John Daly -- Index.
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