Regulation of cellular signal transduction pathways by densensitization and amplification
著者
書誌事項
Regulation of cellular signal transduction pathways by densensitization and amplification
（Wiley series on molecular pharmacology of cell regulation, v. 3）
Wiley, c1994
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Regulation of cellular signal transduction pathways by desensitization and amplification
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Molecular Pharmacology of Cell Regulation Series Editor: Miles D. Houslay This important series provides topical, in-depth and authoritative reviews on all aspects of the molecular mechanisms of cell regulatory processes. It attempts to unravel the molecular structures, properties and functions of systems which provide putative targets for the next generation of drugs. It will, therefore, be of major interest to biochemists, pharmacologists, molecular pathologists,endocrinologists, cell biologists and research clinicians working on the fundamental description of how cells regulate their own and each others activity, on the development of novel therapeutic agents and on analyses of pathological changes and genetic lesions. Volume 3 Regulation of Cellular Signal Transduction Pathways by Desensitization and Amplification Edited by David R. Sibley National Institutes of Health, Bethesda, Maryland, USA and Miles D.
Houslay Institute of Biochemistry, University of Glasgow, UK Amplification and desensitization are well recognized phenomena in signal transduction systems and descriptions of such phenomena are essential in order to gain insight into the coordinated functioning of cells in normal, pathological and transformed states. Written by international experts, this book will appeal to biochemists, pharmacologists and other experimental biologists interested in cellular signalling systems.
目次
Partial table of contents:SENSORY TRANSDUCTION SYSTEMS. Adaptive Responses in Bacterial Chemotaxis (J. Stock). G-PROTEIN-LINKED RECEPTORS. Adrenergic Receptor-Coupled Adenylyl Cyclase Systems: Regulation of Receptor Function by Phosphorylation, Sequestration and Downregulation (S. Liggett R. Lefkowitz). Desensitization of Muscarinic Cholinergic Receptors and the Role of Protein Phosphorylation (M. Hosey). Regulation of Phosphoinositidase C-Linked Receptors and Phosphinositide-Mediated Cell Signaling (R. Wojcikiewicz, et al.). G-PROTEIN REGULATION. Adenosine Receptor/Adenylyl Cyclase Modulation: Heterologous Regulation at the G-Protein Level (V. Ramkumar G. Stiles). PEPTIDE RECEPTORS/TYROSINE KINASES. Regulation of Insulin Receptor Function by Phosphorylation (C. Anderson J. Olefsky). ION CHANNELS. Ligand-Gated Ion Channels: Molecular Structure and Functional Regulation by Phosphorylation (M. Browning S. Rogers). Index.
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