Molecular biology of lung disease
著者
書誌事項
Molecular biology of lung disease
Blackwell Scientific Publications, c1994
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The impact of molecular biology on medicine has been enormous. The techniques of gene sequencing, DNA amplification and cloning have enabled great advances in the diagnosis, treatment and understanding of a variety of diseases. The importance of these new advances is now so great that no doctor can afford to remain uninformed about their relevance to his own field. However, the complex nature of the subject has meant that it has remained relatively impenetrable to the non-specialist. Respiratory medicine is no exception and the editors have recognised the need for a comprehensive survey of the techniques and applications of molecular biology to their own subject aimed at the respiratory physician with no detailed knowledge of the 'new biology'.
目次
- Molecular biology: principles and applications
- Analysis of protein synthesis
- Methods for in situ hybridization
- Finding disease genes
- Protein and gene polymorphisms
- Site directed mutagenesis
- Tissue specificity
- Applications of molecular biology to lung disease: bacterial infection
- Molecular biology and respiratory disease
- Application to pathology
- Oncogenes, cancer and growth factors
- Molecular biology of lung receptors
- The regulation of collagen and elastin gene expression in normal lung and during pulmonary disease
- Transepithelial transport of secretory immunoglobulins
- Heat shock proteins
- Molecular cellular and genetic studies of atopic disease
- Interleukins in the pulmonary inflammatory response
- Gene therapy
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