Mechanisms of immune regulation

Bibliographic Information

Mechanisms of immune regulation

volume editor, Richard D. Granstein

(Chemical immunology, v. 58)

Karger, 1994

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Includes bibliographical references and index

Description and Table of Contents

Description

The dramatic increase in our knowledge of immune processes, which has taken place over recent years, has led to new approaches to the understanding and treatment of disease. The purpose of this book is to present the physiological mechanisms of immune regulation in the light of the new information, and to indicate the effect of this knowledge on selected clinical questions. Among the topics reviewed are T and B cell tolerance, clonal deletion, suppressor cells, mechanisms of immune privileged sites and experimental models of tumour immunity. Oral tolerance, ultraviolet radiation and photosensitized effects on immunity, allograft management, T cell vaccination and regulation of immunity with T cell epitopes are discussed from the point of view of possible therapeutic application. Immunologists, molecular and cell biologists, oncologists, pharmacologists and those working in the pharmaceutical field will find this work of particular interest.

Table of Contents

  • Part 1 Mechanisms of regulation: T cell tolerance, M.S. Vacchio
  • pathways and regulation of B cell responsiveness and tolerance, D.W. Scott, et al
  • regulation of B cell tolerance and triggering by immune complexes, E.R. Fedyk, et al
  • T cell clonal energy, K.M. Gilbert
  • regulation of the immune response with privileged sites, B.R. Ksander and J.W. Streilein
  • suppressor cells and immunity, D.R. Webb, et al. Part 2 Topics of clinical interest: T cell tolerance - models for clinical applications to allergy and autoimmunity, V.C. Schad
  • towards T cell vaccination in rheumatoid arthritis, J.M. van Laar, et al
  • mechanisms of tolerance to allografts, R.S. Lee and H. Auchincloss, Jr
  • oral tolerance - a biologically relevant pathway to generate peripheral tolerance against external and self antigens, A. Friedman, et al
  • mechanisms of ultraviolet radiation carcinogenesis, S. Grabbe and R.D. Granstein
  • regulation of immunity by ultraviolet radiation and photosensitized reactions, M.I. Perez and R.L. Edelson.

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