Filgrastim (r-metHuG-CSF) in clinical practice

Author(s)

    • Morstyn, George
    • Dexter, T. Michael

Bibliographic Information

Filgrastim (r-metHuG-CSF) in clinical practice

edited by George Morstyn, T. Michael Dexter

(Basic and clinical oncology, v. 5)

Dekker, c1994

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

This work describes the preclinical and clinical development of Filgrastim, a bacterially synthesized recominant protein, including its biology, biochemistry, structure and pharmacology. The authors show how Filgrastim can reduce the infectious complications of cancer therapy and discusses its potential in AIDS treatment.

Table of Contents

  • Biology of G-CSF, Graham Molineux and T. Michael Dexter
  • biochemistry and structure of Filgrastim (r-metHuG-CSF), Timothy Osslund and Thomas Boone
  • Pharmacology of Filgrastim (r-metHuG-CSF), Martha E. Vincent et al
  • causes, clinical consequences, and treatment of Neutropenia, Thomas Waits and David H. Johnson
  • use of Filgrastim (r-metHuG-CSF) in severe chronic Neutropenia, David C. Dale et al
  • Filgrastim (r-metHuG-CSF) in the Chemotherapy setting, Susan Blackwell and Jeffrey Crawford
  • use of Filgrastim (r-metHuG-CSF) in human immunodeficiency virus infection, Steven A. Miles
  • the importance of dose in Cancer Chemotherapy and the role of Hematopoietic growth factors, Miguel H. Bronchud
  • Filgrastim (r-metHuG-CSF) in bone-marrow and peripheral blood cell transplantation, Gary Spitzer et al
  • use of Filgrastim (r-metHuG-CSF) in peripheral blood progenitor cell support, Rowan Grant Doig and William P. Sheridan
  • Filgrastim (r-metHuG-CSF) for the treatment of Myelodysplastic Syndromes, Robert S. Negrin and Peter L. Greenberg
  • use of Filgrastim (r-metHuG-CSF) in acute Myeloid Leukemia, Ryuzo Ohno
  • use of Filgrastim (r-metHuG-CSF) in infectious disease, Steve Nelson et al
  • safety profile of Filgrastim (r-metHuG-CSF), Genevieve Decoster et al
  • economic impact of Filgrastim (r-metHuG-CSF), John A. Glaspy et al
  • practical aspects of Filgrastim (r-metHuG-CSF) administration, Debra M. Shoemaker and Mary Ruth Pupa
  • quality of life with Filgrastim (r-metHuG-CSF), Breege Traynor.

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