Alzheimer disease
Author(s)
Bibliographic Information
Alzheimer disease
Raven Press, c1994
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
Written by some of the world's foremost authorities on Alzheimer disease from all relevant basic science fields and clinical specialties, this volume is aims to provide a definitive reference on Alzheimer disease (AD). The book provides an in-depth review of current concepts on every aspect of AD - from its molecular and cellular bases to its inheritance patterns, signs and symptoms, associated anatomic and biochemical pathologies, diagnosis, and therapy. Coverage includes diagnostic criteria, neuropsychology, clinical genetics, epidemiology, and MRI, CT, and PET imaging. Noted investigators discuss current theories on the cell types vulnerable to damage in AD; the underlying alterations in neurotransmitters, neuropeptides, neurotropic factors, receptors, and signal transduction mechanisms; the protein constituents of the neuritic plaques and neurofibrillary tangles; the molecular genetics of AD; and the role of trace elements in its pathogenesis. The book concludes with reviews of clinical trials and experimental therapeutics.
Table of Contents
- Introduction
- the early story of Alzheimer disease
- diagnosis
- psychiatric considerations
- neuropsychology
- clinical genetics of Alzheimer disease
- MRI/CT imaging
- PET imaging
- epidemiology
- clinical aspects of other dementias
- pathology of the other dementias
- plaques, tangles, neurons, and synapses
- topography and architectronics
- neurotransmitters and neuropeptides
- cholinergic systems and related neuropathological predilection patterns in Alzheimer disease
- receptors
- amyloid
- ALZ50,P68, etc.
- Tau protein in Alzheimer disease
- molecular genetics
- brain trace elements in Alzheimer disease
- biochemistry by NMR
- animal models
- altered signal transduction in Alzheimer disease
- neurotrophic factors and neuronal loss - potential relevance to Alzheimer disease
- non-cognitive symptoms in alzheimer disease - definitions, treatments and possible etiologies
- clinical trials in Alzheimer disease
- experimental therapeutics.
by "Nielsen BookData"