Dopamine receptors and transporters : pharmacology, structure, and function

Bibliographic Information

Dopamine receptors and transporters : pharmacology, structure, and function

edited by Hyman B. Niznik

Marcel Dekker, c1994

Available at  / 11 libraries

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Includes bibliographical references and index

Description and Table of Contents

Description

Provides comprehensive coverage of each dopamine receptor transporter system, including up-to-date reviews of the molecular biology, gene evolution, pharmacology, topology, signal transduction properties, anatomical distribution and regulation. The book explains the genetic characterization of the dopamine receptor/transporter gene family and its relationship to the etiology and maintenance of neuropsychiatric disorders, as well as its role in anti-psychotic drug action.

Table of Contents

Part 1 Physiology and Pharmacology of Dopamine Receptors: Dopamine Receptors: Radioligands for Pharmacological and Biochemical Characterization The Neuromodulatory Role of Dopamine in the Teleost Retina Coupling of Dopamine Receptors to Ionic Channels in Excitable Tissues Peripheral Dopamine Receptors Invertebrate Dopamine Receptors. Part 2 Molecular Biology of Dopamine Receptors: Dopamine D1a and D1b Receptors The Dopamine-D2 Receptor The Dopamine-D3 Receptor The Dopamine-D4 Receptor Dopamine Receptor Genes: Promoters and Transcriptional Activation The Evolution of the Dopamine Receptor Gene Family. Part 3 Dopamine Receptors: Structure and Function Molecular Modelling of Dopamine Receptors Dopamine-D1 Receptor: Structure and Function Structure Function Analysis of Dopamine-D2 Receptors by In Vitro Mutagenesis Functional Distinctions of D2Long and D2Short Receptors. Part 4 Anatomical Distribution of the Dopamine Receptor System: distribution of Dopamine D1- and D2-Like Dopamine Receptors in Human Brain Immunocytochemical Localization of D1 and D2 Receptors in Rat Brain Neuroanatomical Distribution of Dopamine Receptor Messenger RNAs. Part 5 Dopamine Receptor/Gene Regulation: Dopamine Receptor Regulation of Immediate-Early Genes in the Basal Ganglia Dopamine Receptor Gene Expression: Effects of Neuroleptics, Denervation, and Development Regulation of D2 Receptor Expression and Function by Epidermal Growth Factor in GH-3 Cells Dopaminergic Signalling and Regulation of Pituitary Hormone Genes The Chakragati Mouse: A Model for Brain Dopaminergic Dysfunction Levels of Functional Interaction Between D1-Like and D2-Like Dopamine Receptor Systems. Part 6 Dopamine Receptors and Molecular Psychiatry: Dopamine Receptors in Schizophrenia Dopamine Receptor and Neurotransmitter Imaging in Psychiatry Illness Molecular Genetics of the Dopamine Receptor Genes and Schizophrenia Dopamine Receptors in Neurological Disease The Dopamine Transporter Molecular Biology of Dopamine Transporters.

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