CiNii 図書 - Oxford textbook of clinical pharmacology and drug therapy

Revised and updated, this second edition retains its essential character. It aims to provide medical students and clinicians with an insight into why drugs have their therapeutic effects, by presenting the basic principles of pharmacology as they affect the human body - the patient. An understanding of these clinical pharmacological principles is essential for rational, safe, effective and economical prescribing. The text shows how knowledge of the scientific basis of drug action is applied in a clinical context to devise the most effective treatments for disease and to maximize the therapeutic effect of the drugs being used. Divided into four sections, this text provides details of adverse drug effects and interactions, pharmacogenetics, clinical trials, the discovery, development and marketing of drugs, drug treatment in the old and the young and the use of drugs in relation to reproduction and pregnancy. It also provides advice on practical matters of drug prescribing. Detailed descriptions of the practical management of diseases with drugs are given, emphasizing the integration of principles with practice. Lastly, a reference pharmacopoeia of over 300 commonly used drugs is presented, which includes details of their uses, modes of actions, pharmacokinetic properties, adverse efects and interacions, doses and regimens. For this edition the format of the original has been retained, but the basic science has been updated and edited to remove any theoretical discussion which is not essential to understanding the therapeutic process. The sections on pregnancy, reproduction and labour have been expanded and updated. The involvement of clinical specialists in the revision of the therapeutic chapters aims to ensure that the book reflects the best clinical practice in these disciplines. This text is aimed at medical students, students of pharmacy and applied pharmacology, nurses in training, newly qualified physicians and those in specialist post-graduate training.

Part 1 Clinical pharmacology - the scientific basis of drug therapy: the four processes of drug therapy
the pharmaceutical process - is the drug getting into the patient?
the pharmacokinetic process - is the drug getting to its site of action?
the pharmacodynamic process - is the drug producing the required pharmacological effect?
practical applications of the analysis of the drug therapy
monitoring drug therapy
pharmacogenetics
adverse reactions to drugs
drug interactions
drug therapy in young and old people
drug therapy and reproduction
patient compliance
placebos
drug discovery and development - the pharmaceutical industry and the regulatory authorities
clinical trials
the drug history and the clinical examination and investigation of drug effects. Part 2 Practical prescribing: principles of prescribing
how to write a prescription
sources of information on drugs. Part 3 The drug therapy of disease: introduction to drug therapy
the drug therapy of infectious diseases, C.P. Conlon and N.J. White
the drug therapy of cardiovascular disorders, T.R. Cripps
the drug therapy of respiratory disorders, J. Efthimiou
the drug therapy of gastrointestinal, hepatic and biliary disorders, H.R. Dalton
drugs and the kidney and the drug therapy of renal, urinary tract, and protatic disorders, J.D. Firth
the drug therapy of endocrine and metabolic disorders, R.M Hillson
the drug therapy of blood disorders, M.E. Haines
the drug therapy of disorders of bones and joints, A.G. Mowatt
the drug therapy of neurological disorders, P.K. Panegyres
the drug therapy of psychiatric disorders, A.J. Wood
the relief of pain, H.J. McQuay
general anaesthesia dnd local anaesthetics, J.W. Sear
drug dependance and abuse, P.J. Robson
the management of poisoning, D.J.M. Reynolds
the principles of cancer chemotherapy, J. Carmichael
immunosuppression and the drug therapy of allergies, connective tissue disorders, and primary immunodeficiencies, G.P. Spickett. Part 4 Pharmacopoeia.

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Oxford textbook of clinical pharmacology and drug therapy

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