Chirotechnology : industrial synthesis of optically active compounds
著者
書誌事項
Chirotechnology : industrial synthesis of optically active compounds
Marcel Dekker, c1993
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This reference provides an introduction to the phenomenon of chirality and its importance in conjunction with biological activity and offers an easy-to-read examination of practical, industrially relevant methods for the synthesis of optically active compounds.;Furnishing hands-on guidelines for the development of economically viable synthetic compounds, Chirotechnology: explains optical isomerism and stereochemistry; gives a general overview of various methods of synthesis; supplies detailed explications of specific techniques, including fermentation, crystallization, the chirality pool, enzymatic methods, and catalytic asymmetric synthesis; illustrates and compares approaches with examples taken directly from industry such as the synthesis of pharmaceuticals, agrochemicals, flavours, and fragrances; and clarifies the importance of determining which approach to use for the synthesis of particular molecules.;With over 1100 literature citations, tables and figures, Chirotechnology is a reference for chemical engineers; industrial, organic and medicinal chemists; and bioprocess technologists, as well as a text for upper-level undergraduate, graduate and continuing-education students in these disciplines.
目次
- Introduction to optical isomerism
- chirality and biological activity
- synthetic methodology
- fermentation processes
- the chirality pool
- racemate resolution via crystallization
- enzymatic transformations
- catalytic asymmetric synthesis
- industrial processes - comparing different approaches
- epilogue - future prospects.
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