Multiparticulate oral drug delivery
著者
書誌事項
Multiparticulate oral drug delivery
(Drugs and the pharmaceutical sciences, v. 65)
M. Dekker, c1994
大学図書館所蔵 全7件
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  佐賀
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This definitive reference explores the various aspects of multiparticulate dosage form development-assessing the in vivo behavior and performance of multiparticulates as well as comparing their market position to other dosage forms.
Discussing-for the first time in a comprehensive manner-alternative pelletization techniques such as balling (spherical agglomeration), spray congealing, and cryopelletization, Multiparticulate Oral Drug Delivery
describes formulation and processing variables that affect the formation, integrity, and performance of coatings derived from molten materials and polymeric solutions and dispersions
analyzes the biopharmaceutical aspects and in vivo performance of multiparticulate drug delivery systems
details the idiosyncrasies of the manufacturing process of hard-shell gelatin capsules
explains the different kinds of packaging materials and machinery and the importance of packaging during the development phase and beyond
previews the marketing considerations of multiparticulate systems in the years to come
presents practical solutions to problems encountered in the area of film-coating processes
and more!
目次
Manufacture of Core Pellets by Balling
Preparation of Micropellets by Spray Congealing
Cryopelletization
Coating of Multiparticulates Using Polymeric Solutions: Formulation and Process Considerations
Coating of Multiparticulates Using Polymeric Dispersions: Formulation and Process Considerations
Coating of Multiparticulates Using Molten Materials: Formulation and Process Considerations,
Suspensions and Dispersible Dosage Forms of Multiparticulates, Roland Bodmeier and Ornlaksana Paeratakul
Multiparticulate Encapsulation Equipment and Process
Compaction of Multiparticulate Oral Dosage Forms
Key Factors in the Development of Modified-Release Pellets
Mechanisms of Release from Coated Pellets
Biopharmaceutical Aspects of Multiparticulates
In Vivo Behavior of Multiparticulate Versus Single-Unit Dose Formulations
Capsule Shell Composition and Manufacturing
Packaging of Multiparticulate Dosage Forms: Materials and Equipment
Marketing Considerations
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