Multiparticulate oral drug delivery

Author(s)

• Ghebre-Sellassie, Isaac

Bibliographic Information

Multiparticulate oral drug delivery

edited by Isaac Ghebre-Sellassie

（Drugs and the pharmaceutical sciences, v. 65）

M. Dekker, c1994

Note

Includes bibliographical references and index

Description and Table of Contents

Description

This definitive reference explores the various aspects of multiparticulate dosage form development-assessing the in vivo behavior and performance of multiparticulates as well as comparing their market position to other dosage forms. Discussing-for the first time in a comprehensive manner-alternative pelletization techniques such as balling (spherical agglomeration), spray congealing, and cryopelletization, Multiparticulate Oral Drug Delivery describes formulation and processing variables that affect the formation, integrity, and performance of coatings derived from molten materials and polymeric solutions and dispersions analyzes the biopharmaceutical aspects and in vivo performance of multiparticulate drug delivery systems details the idiosyncrasies of the manufacturing process of hard-shell gelatin capsules explains the different kinds of packaging materials and machinery and the importance of packaging during the development phase and beyond previews the marketing considerations of multiparticulate systems in the years to come presents practical solutions to problems encountered in the area of film-coating processes and more!

Table of Contents

Manufacture of Core Pellets by Balling Preparation of Micropellets by Spray Congealing Cryopelletization Coating of Multiparticulates Using Polymeric Solutions: Formulation and Process Considerations Coating of Multiparticulates Using Polymeric Dispersions: Formulation and Process Considerations Coating of Multiparticulates Using Molten Materials: Formulation and Process Considerations, Suspensions and Dispersible Dosage Forms of Multiparticulates, Roland Bodmeier and Ornlaksana Paeratakul Multiparticulate Encapsulation Equipment and Process Compaction of Multiparticulate Oral Dosage Forms Key Factors in the Development of Modified-Release Pellets Mechanisms of Release from Coated Pellets Biopharmaceutical Aspects of Multiparticulates In Vivo Behavior of Multiparticulate Versus Single-Unit Dose Formulations Capsule Shell Composition and Manufacturing Packaging of Multiparticulate Dosage Forms: Materials and Equipment Marketing Considerations

by "Nielsen BookData"

Details

• NCID: BA22676878
• ISBN:
  • 0824791916
• LCCN: 94004796
• Country Code: us
• Title Language Code: eng
• Text Language Code: eng
• Place of Publication: New York
• Pages/Volumes: viii, 480 p.
• Size: 24 cm
• Classification:
  • LCC : RS201.N35
  • NLM : W1 DR893B v. 65 1994
  • NLM : QV 785 M961 1994
  • DC20 : 615/.6
• Subject Headings:
  • LCSH : Nanoparticles
  • LCSH : Particles
  • LCSH : Drugs -- Dosage forms
  • LCSH : Oral medication
  • MESH : Dosage Forms
  • MESH : Drug Delivery Systems
  • MESH : Administration, Oral
  • MESH : Drug Design
• Parent Bibliography ID:
  • BA03948165