The chemistry of natural products
著者
書誌事項
The chemistry of natural products
Blackie Academic & Professional, 1993
2nd ed
大学図書館所蔵 件 / 全11件
-
該当する所蔵館はありません
- すべての絞り込み条件を解除する
注記
Includes bibliographical references and index
内容説明・目次
内容説明
The first edition of this book appeared in 1984 and covered the literature until the end of 1982 (one chapter dealt with much of 1983). The present volume is based on the literature published since then until approximately mid-1992. As before, it attempts to highlight the most important advances in all the main areas of natural products research, focusing on structure, chemistry, synthesis, and this time, where appropriate, biosynthesis. Each chapter is necessarily selective but the scope is extended by frequent citation of recent reviews. R. H. T. Contributors Dr C. Bladon Interprobe Chemical Services, Gallowhill House, Larch Avenue, Lenzie, Glasgow G66 4HX, UK Dr M. Gill University ofMelbourne, School ofChemistry, Parkville, Victoria 3052, Australia Dr K. J. Hale University College London, Chemistry Department, Christopher Ingold Laboratories, 20 Gordon Street, London WC1H OAJ, UK Dr R. A. Hill Chemistry Department, University of Glas- gow, Glasgow G12800, UK DrJ. B. Hobbs University of British Columbia, Nucleic Acid- Protein Service Unit, c/o Biotechnology Lab- oratory, Room 237, Westbrook Building, 6174 University Boulevard, Vancouver BC, V6T 1Z3, Canada Dr D. R.
Kelly University of Wales College of Cardiff, School of Chemistry and Applied Chemistry, PO Box 912, Cardiff CF1 3TB, UK DrJ. Leonard Department of Chemistry and Applied Chem- istry, University of Salford, Salford M5 4WT, UK Dr L. R. Milgrom Department of Chemistry, BruneI University, Uxbridge, Middlesex UB8 3PH, UK Ms F. O'Neill Department of Chemistry, Brunei University, Uxbridge, Middlesex UB8 3PH, UK Dr A.
目次
1 Carbohydrates.- 1.1 Introduction.- 1.2 Recent developments in O-glycosidation methodology.- 1.3 Recent developments in C-glycoside synthesis.- 1.4 Synthesis of antibiotic sugars.- 1.5 Use of carbohydrates as chiral templates and reagents for asymmetric synthesis.- 1.5.1 Asymmetric reduction.- 1.5.2 Enantioselective alkylation of carbohydrate derived nucleophiles.- 1.5.3 Enantioselective alkylation of carbohydrate derived electrophiles.- 1.5.4 Monosaccharides as chiral auxiliaries for cycloaddition reactions.- 1.6 Use of carbohydrates as chiral starting materials for the synthesis of enantiomerically pure natural products.- References.- 2 Aromatic compounds.- 2.1 Introduction.- 2.2 Benzenoids.- 2.3 Coumarins.- 2.4 Isocoumarins, chromanones, chromones and cannabinoids.- 2.5 Macrocyclic lactones.- 2.6 Pyrones, butenolides, lignans and benzofurans.- 2.7 Terphenyls.- 2.8 Flavonoids.- 2.9 Xanthones and benzophenones.- 2.10 Naphthalenes and naphthoquinones.- 2.11 Anthraquinones.- 2.12 Anthracyclines.- 2.13 Some other polycyclic antibiotics.- 2.14 Ansamycins.- References.- 3 Terpenoids.- 3.1 Introduction.- 3.2 Monoterpenoids.- 3.3 Sesquiterpenoids.- 3.4 Diterpenoids.- 3.5 Sesterterpenoids.- 3.6 Triterpenoids.- 3.7 Carotenoids.- References.- 4 Steroids.- 4.1 Introduction.- 4.2 Molecular rearrangement.- 4.3 Remote functionalisation.- 4.4 Photochemical reactions.- 4.5 Partial synthesis.- 4.5.1 Oestranes.- 4.5.2 Androstanes.- 4.5.3 Pregnanes.- 4.5.4 Cholanes.- 4.5.5 Cardenolides and bufadienolides.- 4.5.6 Vitamins D.- 4.5.7 Cholestanes and derivatives.- References.- 5 Amino acids, peptides and proteins.- 5.1 Introduction.- 5.2 Amino acids.- 5.2.1 Synthesis.- 5.2.2 New naturally occurring amino acids.- 5.3 Peptides.- 5.3.1 Synthesis.- 5.3.2 Synthesis of glycopeptides.- 5.3.3 Synthesis of phosphorylated peptides.- 5.3.4 Post-translational modifications.- 5.3.5 Design of peptide-based pharmaceuticals.- 5.3.6 New peptides from natural sources.- 5.4 Techniques for structural elucidation.- 5.4.1 X-ray crystallography.- 5.4.2 N.m.r. spectroscopy.- 5.4.3 Molecular modelling.- 5.5 Proteins.- 5.5.1 Incorporation of unnatural amino acids.- 5.5.2 Purification and analysis.- 5.5.3 Sequences, databases and protein folding.- 5.6 Appendix.- 5.6.1 Useful books.- 5.6.2 Databases.- References.- 6 Alkaloids.- 6.1 Introduction.- 6.2 Biomimetic studies.- 6.2.1 Biomimetic synthesis of Iboga and Aspidosperma alkaloids.- 6.2.2 Biomimetic routes to Daphniphyllum alkaloids.- 6.3 Synthesis.- 6.3.1 Reserpine.- 6.3.2 Other yohimbine and heteroyohimbine alkaloids.- 6.4 Marine alkaloids.- 6.4.1 The manzamines.- 6.4.2 Biosynthetic origin of manzamines.- 6.4.3 Total synthesis of manzamine C.- 6.4.4 Synthetic approaches to manzamine A.- References.- 7 Nucleosides, nucleotides and nucleic acids.- 7.1 Introduction.- 7.2 Nucleosides.- 7.2.1 Nucleoside synthesis: general methods.- 7.2.2 Nucleosides containing modified sugars.- 7.2.3 Other nucleosides of interest.- 7.2.4 Some useful and novel reactions.- 7.3 Nucleotides.- 7.3.1 Nucleoside monophosphates and their analogues.- 7.3.2 Cyclic nucleotides.- 7.3.3 Nucleoside polyphosphates and their analogues.- 7.4 Nucleic acids.- 7.4.1 Oligodeoxyribonucleotide synthesis.- 7.4.2 Oligoribonucleotide synthesis.- 7.4.3 Oligonucleotides containing modified internucleotidic links.- 7.4.4 Nucleic acid sequencing.- 7.5 Supplementary reading.- References.- 8 Porphyrins.- 8.1 General introduction.- 8.2 Macrocycle biosynthesis.- 8.2.1 Introduction.- 8.2.2 Substitution pattern of uroporphyrinogen III.- 8.2.3 Biosynthesis of vitamin B12.- 8.3 Haemoprotein model compounds.- 8.3.1 Introduction.- 8.3.2 Supramolecular effects in haemoprotein model compounds.- 8.3.3 Cytochrome P-450 models.- 8.4 Porphyrins with easily oxidisable substituents.- 8.4.1 Introduction.- 8.4.2 Mesotetrakis (3,5-di-t-butyl-4-hydroxyphenyl)porphyrin.- 8.4.3 Mesotetrakis (pyrogallyl) porphyrin.- 8.5 Utilisation of porphyrin excited states.- 8.5.1 Introduction.- 8.5.2 Modelling photosynthesis.- 8.5.3 Solar energy conversion.- 8.6 Porphyrins in photodynamic therapy.- 8.6.1 Introduction.- 8.6.2 Haematoporphyrin derivative, HpD.- 8.6.3 Second generation porphyrins.- 8.6.4 New approaches to photosensitiser delivery.- 8.6.5 Mechanism of photodynamic action.- 8.6.6 Photosensitising porphyrins as herbicides.- 8.7 DNA-porphyrin interactions.- 8.7.1 Introduction.- 8.7.2 DNA cleavage.- 8.7.3 DNA binding.- 8.8 Porphyrins as novel materials.- 8.8.1 Introduction: solid state and liquid crystalline phenomena.- 8.8.2 Porphyrins in molecular electronics.- 8.9 Porphyrins with liquid crystalline properties.- 8.9.1 Introduction.- 8.9.2 Porphyrins with discotic phases.- References.- 9 Aliphatic compounds.- 9.1 Introduction.- 9.2 Semiochemicals.- 9.2.1 Lepidopteran pheromones.- 9.2.2 Methyl substituted aliphatic pheromones.- 9.2.3 Unbridged spiroketals.- 9.3 Development of synthetic technology.- 9.3.1 Bridged spiroketal semiochemicals of bark beetles.- 9.3.2 Organosulphur semiochemicals.- 9.4 Marine natural products.- 9.4.1 Palytoxin.- 9.4.2 Okadaic acid, dinophysistoxins and acanthifolicin.- 9.4.3 Fused ring polyethers.- 9.5 Enyne-allene and enediyne antibiotics.- 9.5.1 Neocarzinostatin.- 9.5.2 Trisulphide triggered enediyne antibiotics: the esperamicins and calicheamicins.- 9.5.3 Dynemicins.- References.- Chemical abbreviations and acronyms.
「Nielsen BookData」 より