Monoclonal antibodies and peptide therapy in autoimmune diseases
著者
書誌事項
Monoclonal antibodies and peptide therapy in autoimmune diseases
（Immunology series, v. 59）
M. Dekker, c1993
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Combining principles of modern immunology with applications to immunopathology, this reference documents developments in the immunotherapy of autoimmune diseases - emphasizing monoclonal antibody and peptide approaches. Detailing possible antigen-specific manoeuvres, from targeting the T-cell receptor itself to intervening at the level of the major histocompatibility complex (MHC) antigens, "Monoclonal Antibodies and Peptide Therapy in Autoimmune Diseases": provides an update on T-cell basic science; discusses most monoclonal antibodies used in autoimmune disease experiments; describes the concept of peptide therapy in its various forms; and presents fundamental pharmacological data that clarify the clinical usage of these new agents. Containing over 1100 literature citations, "Monoclonal Antibodies and Peptide Therapy in Autoimmune Diseases" should be a useful resource for immunologists, rheumatologists, pharmacologists, pathologists, dermatologists, nephrologists, and graduate and medical school students in these disciplines.
目次
- Part 1 Basis for monoclonal antibody and peptide therapy: the nature of B- and T-cell determinants, Akio Ametani and Eli E. Sercarz
- molecular dissection of the T-cell receptor/CD3 complex, Bernard Malissen et al
- CD4, CD8 and other surface molecules regulating T-cell activation, Jean-Pierre Revillard and Nathalie Berard-Bonnefoy
- MHC proteins and MHC peptide interactions, Dominique J. Charron and Vincent Lotteau
- monoclonal antibodies for the therapeutic induction of tolerance, Herman Waldmann et al
- T-cell receptor-based immunointervention in autoimmune diseases - therapeutic use of monoclonal antibodies, Lucienne Chatenoud and Jean-Francois Bach. Part 2 Mechanisms of autoimmune diseases: the role of autoantigens in the driving of autoimmune diseases, Ivan M. Roitt
- T-cell receptors in autoimmune disease, Hans Acha-Orbea
- MHC and autoimmune diseases, Gerald T. Nepom. Part 3 T-cell receptor-based immunointervention in autoimmune diseases: anti-TcR antibodies in autoimmune diseases, Christian Boitard and Jean-Francois Bach
- anti-CD3 antibodies, Lucienne Chatenoud and Jean-Francois Bach
- anti-T-cell receptor V8 antibodies in autoimmunity, Hans Acha-Orbea
- vaccination with T-cell receptor peptides, Steven Brostoff. Part 4 Anti-CD4 antibodies: treatment of murine lupus with anti-CD4 monoclonal antibodies, David Wofsky
- anti-CD4 antibodies in diabetes, Judith A. Shizuru and C. Garrison Fathman
- from treatment of experimental allergic encephalomyelitis to clinical trials in multiple sclerosis, Lawrence Steinman et al
- human-murine chimeric CD4 monoclonal antibodies - a modern panacea for autoimmune disease, Gert Riethmuller et al
- CD4 antibody therapy in chronic inflammatory dermatological diseases, P. Morel et al. Part 5 Other monoclonal antibodies: anti-class II antibody treatment in autoimmune diseases, Christian Boitard
- interleukin-2 receptor-targeted immune therapy, T. Diamantstein and Hans Juergen Hahn
- anti-gamma interferon (IFN-gamma) monoclonal antibodies, Jean-Francois Bach. Part 6 Autoantigens: suppression of T-cell activation by administration of MHC class II-binding peptides, Luciano Adorini and Jean-Charles Guery
- autoantigenic peptide therapy in experimental autoimmune encephalomyelitis, David C. Wraith
- thyroglobulin as autoantigen and tolerogen, David C. Rayner et al
- prevention of myosin-induced autoimmune myocarditis with competitor peptides, Stacy C. Smith and Paul M. Allen. Part 7 Summary: summary of monoclonal antibody and peptide therapy, Jean-Francois Bach.
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