Modern trends in human leukemia VII : new results in clinical and biological research including pediatric oncology
著者
書誌事項
Modern trends in human leukemia VII : new results in clinical and biological research including pediatric oncology
（Haematology and blood transfusion = Hämatologie und Bluttransfusion, 31）
Springer-Verlag, c1987
- : gw
- : us
- 統一タイトル
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Blut. Supplement
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注記
Includes bibliographies and index
"Supplement to Blut"--T.p. verso
内容説明・目次
内容説明
Ideo autem omnes ad consilium vocari diximus, quia saepe iuniori Dominus revelat quod melius est. * Benedictus de Nursia Regula Benedicti, ca. 550 A. c. Caput III,3 The Wilsede Meetings were initiated in 1973 as an unusual experiment, and in the meantime this biennial symposium has already come to constitute an established and successful tradition. In June 1986 scientists and physicians met for the seventh time in the 3- year-old Emmenhof in Wilsede, in the heart of the Liineburg Heath, to dis- cuss modern trends in human leukemia. It was Pappenheim who in 1910 prepared the first international hematol- ogy congress. It was to have been held in Berlin under the title "Der groBe mononukleiire Leukozyt Ehrlichs, seine Morphologie und Funktion, seine Herkunft und seine Benennung" (Ehrlich's large mononuclear leukocyte. Its morphology, function, origin, and name), which was the most important and topical question at that time. It is amazing to think that as early as 1900, thanks to the pioneering research of Maximov and the innovative staining method developed by Ehrlich, the differentiation of the blood cells had, to a large extent, already been discovered.
It is a sad fact that this congress never took place due to personal controversies among leading hematol- ogists, especially between Pappenheim and the Austrian hematologist Tiirk. Fortunately the Wilsede Meetings have never incurred this type of per- sonal controversies. On the contrary, both matter-of-fact discussions at a high scientific level and the development of personal friendships have always characterized their singular atmosphere.
目次
- Frederick Stohlmann Jr. Memorial Lecture.- for Harald zur Hausen.- Viruses in Human Tumors.- for Donald Metcalf.- Hemopoietic Growth Factors and Oncogenes in Myeloid Leukemia Development.- New Strategies in Leukemia Diagnostic and Therapy.- Poster Award for U. Creutzig.- Treatment Results in Childhood AML, with Special Reference to the German Studies BFM-78 and BFM-83.- The Treatment of Acute Myelogenous Leukemia.- Long-term Follow-up After Therapy Cessation in Childhood Acute Lymphoblastic Leukemia.- Progress in Treatment of Advanced Non-Hodgkin's Lymphoma in Children - Report on Behalf of the Polish Children's Leukemia/Lymphoma Study Group.- Strategies for the Future Chemotherapy of Human Immunodeficiency Virus (HIV).- Intraarterial Cis-platinum in Osteosarcoma.- In Vitro Treatment of Bone Marrow from Patients with T-Cell Acute Lymphoblastic Leukemia and Non-Hodgkin's Lymphoma Using the Immunotoxin Wtl-Ricin A.- Ablative Therapy Supported by Autologous Bone Marrow Transplantation with In Vitro Treatment of Marrow in Patients with B-Cell Malignancy.- Use of Autologous Bone Marrow Transplantation in Acute Myeloid Leukemia.- Monoclonal-Antibody-Purged Autologous Bone Marrow Transplantation for Relapsed Non-T-Cell Acute Lymphoblastic Leukemia in Childhood.- The Use of Cultured Bone Marrow Cells for Autologous Transplantation in Patients with Acute Myeloblastic Leukemia.- Bone Marrow Transplantation in Leukemia in the Absence of an HLA-Identical Sibling Donor.- Bone-Marrow Purging with Monoclonal Antibodies and Human Complement in ALL and AML.- Purging of Bone Marrow with a Cocktail of Monoclonal Antibodies (VIB-pool) for Autologous Transplantation.- Autologous Bone Marrow Transplantation in Paediatric Solid Tumours.- Cytokines with Possible Clinical Utility.- Biological Approaches to Cancer Therapy.- IL-2 Receptors in Adult T-Cell Leukemia: A Target for Immunotherapy.- Application of Interleukin 2 in Neuroblastoma.- Biologic Agents for the Management of Hematological Disorders: Chronic Myeloid Leukemia.- Human B-Cell Growth and Differentiation Factors, and Their Effects on Leukemic B-Cells.- Production of Three Monoclonal Antibodies -A01, B05, and C11-Against B-Cell Leukemia.- Natural Killer Activity in Preleukemic States.- Some Karyotypic Aspects of Human Leukemia.- Nonisotopic In Situ Hybridization for Mapping Oncogenic Sequences.- Persistence of CML Despite Deletion of Rearranged bcr/c-abl Sequences.- Similar Molecular Alterations Occure in Related Leukemias With and Without the Philadelphia Chromosome.- Rearrangement of the bcr Gene in Philadelphia-Chromosome-Negative Chronic Myeloid Leukemia.- Rearrangement of bcr and c-abl Sequences in Ph-positive Acute Leukemias and Ph-negative CML - an Update.- Molecular Cloning and Serological Characterization of an Altered c-abl Gene Product Produced in Ph1 CML Patients.- Human Follicular Lymphomas: Identification of a Second t (14
- 18) Breakpoint Cluster Region.- Amino Acid Substitution at Position 13 of the N-ras Gene in a Non-Hodgkin's Lymphoma Patient.- Loss of Hematopoietic Progenitor Cells CFU-GEMM, BFU-E, CFU-Mk, and CFU-GM in the Acquired Immunodeficiency Syndroms (AIDS)?.- Sensitivity of Stromal Elements from Human Bone Marrow Cells to Cytosine Arabinoside In Vitro.- The Secretion of Plasminogen Activators by Human Bone Marrow Progenitor Cells.- Leukemic Colony-Forming Cells in Acute Myeloblastic Leukemia: Maturation Hierarchy and Growth Conditions.- Hexosaminidase I Indicates Maturation Disarrangement in Acute Leukemias.- Membrane-Microfilament Interactions in the Cells of B-Chronic Lymphocytic Leukemia.- Cell Biology.- ts-Oncogene-Transformed Erythroleukemic Cells: A Novel Test System for Purifying and Characterizing Avian Erythroid Growth Factors.- Biological Activities of Recombinant Human Granulocyte Colony-Stimulating Factor (rhG-CSF) and Tumor Necrosis Factor: In Vivo and In Vitro Analysis.- Molecular Properties and Biological Activity of Human Macrophage Growth Factor, CSF-1.- Regulatory Control of the Epidermal Growth Factor Receptor Tyrosine Kinase.- Cellular Speciflty and Molecular Characteristics of the Binding of Colony-Stimulating Factors to Normal and Leukemic Cells.- Fractionation of CSF Activities from Human Placental Conditioned Medium.- Prolifer-ative Effects of a Recombinant Human Granulocyte Colony-Stimulating Factor (rG-CSF) on Highly Enriched Hematopoietic Progenitor Cells.- The myc Oncogene and Lymphoid Neoplasia: From Translocations to Transgenic Mice.- Cloning of Human Thymic Subcapsular Cortex Epithelial Cells by SV40 ori-Transfection.- v-H-ras Gene Reduces IL-3 Requirement in PB-3c Mastocytes In Vitro Followed by Autokrine Tumor Formation In Vivo.- Modification of Oncogenicity of Tumor Cells by DNA-Mediated Gene Transfer.- A Human Leukemic T-Cell Line Bears an Abnormal and Overexpressed c-myc Gene: Molecular and Functional Characterization of the Rearrangement.- Association of the Heme-Controlled eIF-2? Kinase with Spectrin-Derived Peptides.- Involvement of the Membrane Skeleton in the Regulation of the cAMP-Independent Protein Kinase and a Protein Phosphatase that Control Protein Synthesis.- Lineage Determination During Haemopoiesis.- Clinical Implications of Tumor Heterogeneity.- Tumour Cell Heterogeneity and the Biology of Metastasis.- Cancer Clonality and Field Theory.- Leukemia Progression: Role of Tissue Disorganization.- The Nucleoskeleton: Active Site of Transcription and Replication.- Immunology.- Henry Kaplan Award for H. J. Stauss.- Identification of a Gene Encoding a Tumor-Specific Antigen that Causes Tumor Rejection.- Formation of a Hybrid bcl-2/Immuno-globulin Transcript as a Result of t (14
- 18) Chromosomal Translocation.- Involvement of the D Segment (DQ52) Nearest to the JH Region in Immunoglobulin Gene Rearrangements of Lymphoid-Cell Precursors.- Pattern Recognition Among T-Cell Epitopes.- Regulation of Ig Gene Expression in Murine B-Lymphocytes.- Isolation, Biochemical Analysis and N-terminal Amino Acid Sequence of a Cell Surface Glycoprotein that Binds to the "Erythrocyte Receptor" of T-Lymphocytes.- The Regulation of T-Cell Proliferation: A Role for Protein Kinase C.- Activation of Natural Killer Function Through the T11/E Rosette Receptor.- Tumor Necrosis Factor: A Potent Mediator of Macrophage-Dependent Tumor-Cell Killing.- Organ-Associated Macrophage Precursor Cells as Effector Cells Against Tumor Targets and Microorganisms.- Immune Functions and Hematopoietic Progenitor Cell Activity in Plasmacytoma-Bearing Mice Cured by Melphalan.- Recombinant Vaccinia Viruses as Live Vaccines.- use of Fluorescence-Activated Cell Sorting to Select Hybrid Hybridomas Producing Bispecific Monoclonal Antibodies.- Virology.- Henry Kaplan Award for J. C. Neil.- Viral Transduction of Host Genes in Naturally Occuring Feline T-Cell Leukaemias: Transduction of myc and a T-Cell Antigen Receptor ?-Chain Gene.- Analysis of the Biological Role of Human Papilloma Virus (HPV)-Encoded Transcripts in Cervical Carcinoma Cells by Antisense RNA.- Transcription of Human Papillomavirus Type-18 DNA in Human Cervical Carcinoma Cell Lines.- Are Haematophagous Insects Vectors for HTLV-I?.- Neutralization and Receptor Recognition of Human T-Lymphotropic Retroviruses.- Markers of HTLV-I-Related Virus in Hamadryas Baboon Lymphoma.- Replication and Patho-genesis of the Human T-Cell Leukemia/Lymphotropic Retroviruses.- Complete Nucleotide Sequences of Functional Clones of the Virus Associated with the Acquired Immunodeficiency Syndrome, HTLV-III/LAV.- LAV/HTLV-III: Fine-Structure Analysis, Localization of Structural Proteins, and Detection of Envelope Antigens by Patient Sera.- Transfusion-Acquired HIV Infection Among Immunocompromised Hosts.- Restricted Neutralization of Divergent HTLV-III/LAV Isolates by Antibodies to the Major Envelope Glycoprotein.- Interaction of Viral and Cellular Factors with the HTLV-III LTR Target Sequences In Vitro.- Improvement of HIV Serodiagnosis.- Incidence of LAV/HTLV-III-Positive Blood Donors.- Growth of the HTLV-III Strain of Human Immunodeficiency Virus in Different Cell Types.- Nonhuman Primate Models of Human Hematological Malignancies.- Modelling of Malignant Lymphoma in Rabbits, Using Oncogenic Viruses of Non-Human Primates.- Retro-virus-induced Malignant Histiocytosis in Mice: A Model for the Human Disease.- Oncogenes: Clinical Relevance.- Retroviruses with Two Oncogenes.- Activation of the met Proto-Oncogene in a Human Cell Line.- Molecular-Genetic Analysis of myc and c-Ha-ras Proto-Oncogene Atterations in Human Carcinoma.- Interaction of Promoters and Oncogenes During Transfection.- Conversion of ras Genes to Cancer Genes.- Identification of the Bovine Leukemia Virus Transactivating Protein (p34x).- Monoclonal Antibodies Against the Viral and Human Cellular myb Gene Product.- Atavistic Mutations Reflect the Long Life Span of Dispensable Genes.- Cancer Genes Generated by Rare Chromosomal Rearrangments Rather than Activation of Oncogenes.- Repetition as the Essence of Life on this Earth: Music and Genes.
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