5-hydroxytryptamine-3 receptor antagonists

Bibliographic Information

5-hydroxytryptamine-3 receptor antagonists

edited by Frank D. King, Brian J.Jones, Gareth J. Sanger

CRC Press, c1994

Other Title

Five-hydroxytryptamine-three receptor antagonists

Available at  / 2 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

5-Hydroxytryptamine-3 Receptor Antagonists provides a comprehensive, authoritative review of the topic featuring contributions by recognized leaders in the field. The book's three sections cover compound discovery and activity rationalization, the use of compounds for studying 5-HT3 receptors, and their applications to therapeutics. This book will be an important reference for oncologists, researchers working with the CNS and gastrointestinal disorders, and anyone working in the 5-HT field within the pharmaceutical arena, academia, and medical practice.

Table of Contents

Structure Activity Relationships of 5-HT3 Receptor Antagonists (F.D. King). Molecular Modeling Studies of the 5-HT3 Antagonist Recognition Site (M.F. Hilbert). Assay Techniques for Measuring 5HT3 Receptor Antagonist Activity (G.J. Sanger and B.J. Jones). Localization of 5-HT3 Receptors (R.A. Leslie, D.J.M. Reynolds, and N.R. Newberry). Molecular Characterization of 5-HT3 Receptors (S.C.R. Lummis, G.J. Kilpatrick, and I.L. Martin). Electrophysiological Studies of 5-HT3 Receptors (J.A. Peters, J.J. Lambert, and H.M. Malone). 5-HT3 Receptor Antagonists in Anxiety (B.J. Jones and D.C. Piper). 5-HT3 Receptor Antagonism and Schizophrenia (B. Costall and R.J. Naylor). 5-HT3 Receptor Antagonists in the Treatment of Cognitive Disorders (B. Costall and R.J. Naylor). 5-HT3 Receptor Antagonists, Reward and Drug Withdrawal (S.J. Cooper and D.B. Gilbert). Role of 5-HT3 Receptors in Nociception (J.R. Fozard). 5-HT3 Receptor Antagonists and Anti-Emesis (P.L.R. Andrews). The Role of the 5-HT3 Receptor in Normal and Disordered Gastrointestinal Function (G.J. Sanger, S.E. Banner, and K.A. Wardle).

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