Mechanisms of protein folding
著者
書誌事項
Mechanisms of protein folding
（Frontiers in molecular biology）
IRL Press, c1994
- : hbk
- : pbk
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注記
Includes bibliographical references and index
内容説明・目次
- 巻冊次
-
: hbk ISBN 9780199633968
内容説明
Although scientists are aware that proteins and enzymes consist of strings of amino acids, they are still trying to discover how the one-dimensional string folds into a 3D structure that functions biologically. This account of their search explores its industrial and medical importance.
目次
- The protein folding problem
- The early stages of folding
- The contribution of the molten globule model
- Proline isomerization as a rate-limiting step
- The formation of native disulfide bonds
- Assembly of multi-subunit structures
- How the protein folds in the cell
- Protein folding in biotechnology.
- 巻冊次
-
: pbk ISBN 9780199633975
内容説明
The past five years have seen a giant leap forward in our understanding of the way proteins fold into their three dimensional, functional conformations.
In this volume a group of leading scientists in the field review and assess the experimental evidence that underpins these advances and look for signs of a general picture of how proteins fold. They show how these major conformational changes are leading to new insights into other fields such as membrane translocation and pore formation as well as the clinically important aggregation phenomena.
A valuable handbook which will be essential for all fascinated by the power and flexibilty of proteins.
目次
- (i) The protein folding problem
- (ii) The early stages of folding
- (iii) The contribution of the molten globule model
- (iv) Proline isomerization as a rate-limiting step
- (v) The formation of native disulfide bonds
- (vi)
- (vii) Assembly of multi-subunit structures
- (viii) How the protein folds in the cell
- (ix) Protein folding in biotechnology
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