The SAM model of senescence : proceedings of the first International Conference on Senescence : the SAM model, Kyoto, 17-18 March 1994
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Bibliographic Information
The SAM model of senescence : proceedings of the first International Conference on Senescence : the SAM model, Kyoto, 17-18 March 1994
(International congress series, no. 1062)
Excerpta Medica, 1994
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Includes index
Description and Table of Contents
Description
A summary of studies using Senescence Accelerated Mouse (SAM). Research on SAM is directed to investigations on the pathogenesis of age-associated disorders; on effective methods to modulate the advance of senescence; and on the underlying mechanisms in primary ageing processes.
Table of Contents
- Part 1 Animal models for research on ageing: comparative perspectives on phenotypic plasticity in the SAM mouse strains and other animals, C.E. Finch
- senescence accelerated mouse (SAM)
- a novel murine model of ageing, T. Takeda et al. Part 2 Topics in SAM research: murine senile amyloidosis and accelerated senescence, H. Naiki
- molecular genetic studies on SAM, K. Higuchi. Part 3 Neuroscience in ageing and SAM research: characteristics of memory and behavioral disorders in SAMP8 mice, M. Miyamoto
- neurochemical studies on ageing in SAM brain, Y. Nomura et al. Part 4 Cellular, molecular, biochemical and physiological aspects of senescence: molecular biological study of the AKR-type thymoma in SAM, L. Mio et al
- serum lipid peroxide level of the senescence-accelerated mouse, S. Komura et al. Part 5 Immunology and senescence: genetic control of defective helper T cell activity in in vitro antibody responses in short-lived SAM mice, K. Hanada et al
- abnormalities of B cells and dendritic cells in SAMP1 mice, H. Haruna et al. Part 6 Periodontal tissue and joints: cytokins in bone marrow of SAMP6/Ta, K. Yoh et al
- metal concentrations in liver, kidney and femur of SAMP6/Ta, N. Koizumi and R. Ninomiya. Part 7 Sensory organs: morphological study on cataractous lens of senescence accelerated mouse (SAM), H. Nishimoto et al
- age-related hearing impairment in senescence-accelerated mouse (SAM), Y. Saitoh et al. Part 8 Lung, reproductive organs and amyloidosis: a novel model of ageing lung, Y. Fukuchi et al
- quantitative studies on spermatogenesis in the senescence accelerated mouse, H. Miyamoto et al. Part 9 Neurobiology I - development and degeneration: electrophysiological and morphological studies of SAMP10 frontal cortex neurons, H. Nakanishi et al
- changes with age in the mineral status in brain of female SAMP1 and SAMR1, A. Morita et al. Part 10 Neurobiology II - cell biology, excitable membrane and synaptic transmission: relationship between radiation and acceleration of ageing, M. Iseki et al
- ultrastructural study of PAS-positive granular structures (PGS) in brains of SAMP8, M. Irino et al. Part 11 Neurobiology III - neural basis of behavior: deficit of short-term memory in SAMP8, A. Ohta et al
- studies on genetic aspects of impaired learning and memory in SAMP8 mice, J.F. Flood and J.E. Morley. Part 12 Amelioration of impaired learning ability: FGF facilitation of learning and memory and protection from memory loss in senescence accelerated mice, Y. Oomura et al
- effects of cholinomimetics on the disturbance of passive avoidance response in senescence-accelerated mice, M. Suzuki et al. (Part Contents).
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