Quinolone antimicrobial agents

著者

• Hooper, David C.
• Wolfson, John S.

書誌事項

Quinolone antimicrobial agents

edited by David C. Hooper and John S. Wolfson

american Society for Microbiology, c1993

2nd ed

注記

Wolfson names appears first on the earlier edition

Includes bibliographical references and index

内容説明・目次

内容説明

Quinolones remain the most important class of antimicrobial agents discovered in recent years - over 1000 have been synthesized and evaluated. Since the publication of the original edition, considerable strides have been made in the research on structure-activity relationships, mechanism of action, resistance, pharmacodynamics and drug interactions.

目次

• Introduction
• Structure-Activity relationships
• Mechanisms of quinolone action and bacterial killing
• Quinolone-DNA interaction
• Mechanisms of bacterial resistance to quinolones
• Clinical resistance in clinical practice: occurrence and importance
• Quinolones and eukaryotic topoisomerases
• Activity in vitro of the quinolones
• Pharmacokinetics and tissue concentrations in normal persons
• Pharmacokinetics of fluoroquinolones in selected populations
• Drug-drug interactions with fluoroquinolone antimicrobial agents
• Pharmacodynamics of the fluoroquinolones
• Treatment of urinry tract infections with quinolone antimicrobial agents
• Role of quinolones in treatment of chronic bacterial prostatitis
• Use of quinolones in sexually transmitted diseases
• Use of the quinolones for treatment and prophylaxis of bacterial gastrointestinal infections
• Treatment of respiratory tract infections with quinolone antimicrobial agents
• Treatment of infections of the ears, nose and throat, and nasal carriage
• Use of quinolones for treatment of osteomyelitis and septic arthritis
• Treatment of bacterial meningitis
• Treatment of experimental and human bacterial endocarditis with quinolone antimicrobial agents
• Treatment of skin and soft tissue infections with quinolone antimicrobial agents
• Treatment of eye infections
• Use of quinolone antimicrobial agents in immunocompromised patients
• Veterinary use of quinolones
• Adverse effects
• Effects of quinolones on the central nervous system
• Effetcs of quinolones on the immune system
• Conclusions and summary

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA23546266
• ISBN:
  • 1555810594
• LCCN: 93010990
• 出版国コード: us
• タイトル言語コード: eng
• 出版地: Washington, D.C.
• ページ数/冊数: xiv, 549 p.
• 大きさ: 27 cm
• 分類:
  • LCC : RM666.Q55
  • NLM : QV 250 Q66 1993
  • DC20 : 616.9/2061
• 件名:
  • LCSH : Quinolone antimicrobial agents -- Testing
  • LCSH : Bacterial diseases -- Chemotherapy -- Evaluation
  • MESH : Anti-Infective Agents, Quinolone -- pharmacology
  • MESH : Bacterial Infections -- drug therapy
  • MESH : Quinolinones -- pharmacology