The Keratinocyte handbook

著者

書誌事項

The Keratinocyte handbook

Irene M. Leigh ... [et al.]

Cambridge University Press, c1994

大学図書館所蔵 件 / 全8件

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注記

Includes index

内容説明・目次

内容説明

Keratinocytes, as the main cellular component of the organism/environment interface, perform a vast range of functions in protection, secretion, sensation and self-repair by virtue of their great plasticity in form and development. Indeed recent medical advances in laboratory culture of these cells for use as skin grafts in cases of severe burns or ulceration owe much of their success to this very plasticity. Drawing upon a wide range of international expertise the various interconnected aspects of cell structure, composition and function are laid out in this volume, providing a comprehensive dossier of the keratinocyte and its biological significance. Together with its companion volume Keratinocyte Methods (available in the shrinkwrapped set) it will prove invaluable reading for all encountering keratinocytes in both laboratory and clinic.

目次

  • Introduction
  • 1. Ultrastructure of the epidermis Karen Holbrook
  • Part I. Keratinocyte Culture Systems: 2. Growth of human keratinocytes with feeder cells Irene Leigh and Fiona Watt
  • 3. Defined culture systems for epidermal keratinocytes Rebecca Morris and Susan M. Fischer
  • 4. Epithelial-mesenchymal interactions control keratinocyte growth and differentiation Norbert Fusenig
  • 5. Keratinocyte-melanocyte interactions in in vitro reconstituted normal human epidermis Michele de Luca, Sergio Bondanza, Eddi di Marco, Pier Carlo Marchisio, Fiorella D'Anna, Adriano Tito Franzi and Ranieri Cancedda
  • 6. Human pilosebacious culture: the background Terence Kealey and Michael P. Philpott
  • 7. The development and differentiation of embryonic and fetal keratinocytes Chris Fisher
  • Part II. Keratinocyte Biology: Section 1. Adhesion: 8. Integrins and other cell adhesion molecules Fiona Watt and Mark D. Hertle
  • 9. Desmosomes and hemidesmosomes Pamela Cowin
  • 10. Basement membrane proteins Jo-David Fine
  • Section 2. Proliferation and keratinocyte differentiation: 11. Cell kinetics of keratinocytes and stem cells Robin Dover
  • 12. Measurement of specific mRNA content of different sizes in relation to growth differentiation Jeffrey Teumer, Kathleen Zezulak and Howard Green
  • 13. Epidermal-mesenchymal interactions Ian C. Mackenzie
  • 14. Transglutaminases in keratinocytes Robert H. Rice, Majid Mehrpouyan, Qin Qin and Marjorie A. Phillips
  • 15. Envelope precursors Marcia Simon
  • 16. Keratinocyte cytoskeleton Susan M. Morley and E. Birgitte Lane
  • 17. Keratohyalin granules Beverly A. Dale, Katheryn A. Resing and Richard B. Presland
  • 18. Epidermal biosynthesis Maria Ponec
  • 19. Keratinocytes and immunological cytokines Tom J. Stoof, Dick M. Borrma and Brian J. Nickoloff
  • 20. Differentiation in hard keratin tissues: hair and related structures B. C. Powell and G. E. Rogers
  • Section 3. Transformation: 21. Human papillomavirus mediated cell transformation Alan Storey, Connie Sexton and Lawrence Banks
  • 22. Oncogenes and skin cancer Ximena Montano
  • 23. Transgenic mouse skin defects David A. Greenhalgh, Joseph A. Rothnagel, Andrea M. Dominey, Xiao-Jing Wang and Dennis R. Roop
  • 24. In vitro transformation and tumour progression: a multistep model for skin carcinogenesis Petra Boukamp, Dirk Breitkreutz, Andrea Hulsen, Pascal Tomakisi and N. E. Fusenig
  • Part III. Keratinocyte Clinical Applications: 25. Keratinocyte allografting and wound healing Irene Leigh
  • 26. Keratinocyte grafting - animal models Caroline Compton
  • 27. Keratinocytes in the diagnosis of genetic disorders Robin A. J. Eady, Akemi Ishida-Yamamoto and John A. McGrath
  • 28. Epithelial gene therapy Lorne B. Taichman.

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