The Discovery of natural products with therapeutic potential

著者

    • Gullo, Vincent Philip

書誌事項

The Discovery of natural products with therapeutic potential

edited by Vincent P. Gullo

(Biotechnology series, 26)

Butterworth-Heinemann, c1994

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sources of natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.

目次

  • The source of Chemical Diversity
  • Aerobic Actinomycetes: A Continuing Source of novel Natural Products, Bacterias a Source of Novel Therapeutics, The Potential of Fungi in the Discovery of Novel, Low Molecular Weight pharmaceuticals, Discover of Drugs from Higher Plants, The Discovery of Marine Natural Products with therapeutic Potential, New Targets for Screening Assays, Mechanism-Based Screening for the Discovery of Novel Antifungals, Strategies for Discovering Antiviral Agents from Natural Products, Mechanism - based Screens in the Discovery of Chemotherapeutic Antibacterials, Oncogene Function Inhibitors of Microbial Origin, Screening Methodologies for the Discovery of Novel Cytotoxic antitumor Agents, hypocholesterolemic Agents, Immunomodulators, Isolation and Structure Determination of Natural products
  • Isolation and purification of Secondary Metabolities, Moderm Spectroscopic Approaches to Structural Eluicidation.

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