Selection and handling of animals in biomedical research
Author(s)
Bibliographic Information
Selection and handling of animals in biomedical research
（Handbook of laboratory animal science / edited by Per Svendsen, Jann Hau, v. 1）
CRC Press, c1994
Available at 31 libraries
Note
Includes bibliographical references and index
Description and Table of Contents
Description
This two-volume set presents a comprehensive description of laboratory animal genetics, diseases, health monitoring, nutrition, and the environmental impact on animal testing. It considers the ethics of animal experimentation through a complete review of European and North American legislation on the topic. It discusses alternatives to animal experiments, including the use of isolated organs, cell cultures, and computer simulations.
The book also examines general methods, including experimental design and statistical evaluation, non-surgical and surgical techniques, anesthesia, and post-mortem examinations. Reviews of animal models for studying diseases of different organ systems, infectious diseases, cancer, and toxicology are featured as well.
Table of Contents
General Aspects: Animal Research and Ethics (P. Sandoe). European Legislation on the Use of Live Animals for Scientific Research (S. Erichsen). North American Legislation and Regulation of the Use of Live Animals for Scientific Research (M.B. Dennis, Jr. and G.L. Van Hoosier, Jr.). Good Laboratory Practice (B. Lissau). Classification of Animal Experiments (K.J. Obrink). Laboratory Animal Science Associations (O. Kugelberg and L. Wass). Allergies to Laboratory Animals (S. Hunskar and R. Fosse). Zoonoses (A. Detmer). Laboratory Animal Facilities (D.R. Sorensen). Selection of Laboratory Animals: Laboratory Animal Genetics and Genetic Monitoring (F. Dagnaes). Health Status and the Effects of Microbial Organisms on Animal Experiments (A.K. Hansen). Health Monitoring (C. Rehbinder). Nutrition and the Importance of Nutrients to Animal Experiments (A. Chwalibog). Environmental Impact on Animal Experiments (P. Svendsen). Experimental Methods: Experimental Design and Statistical Evaluation (A. Volund). Common Non-Surgical Techniques and Procedures (K. Iwarson, L. Lindberg, and T. Waller). Gnotobiology (A. Hem). Monoclonal and Polyclonal Antibodies (K. Erb and J. Hau). Laboratory Animal Anesthesia (P. Svendsen). The Treatment of Pain and Suffering in Laboratory Animals (A. Smith). Surgical Procedures (H.P. Olesen). Microsurgical Procedures in Experimental Research (D.A. Steinbruchel). Post-Mortem Procedures (R. Feinstein). Alternatives to Animal Experiments: Isolated Organs as Replacements for Vertebrate Animals (J.J. Holst). Cell Cultures as Replacements for Vertebrate Animals (K. Pelkonen). Computers as Alternatives to Animals in Biomedical Education, Research, and Testing (R. Fosse).
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