Bibliographic Information

Animal models

edited by Per Svendsen and Jann Hau

(Handbook of laboratory animal science / edited by Per Svendsen, Jann Hau, v. 2)

CRC Press, c1994

Available at  / 30 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

This two-volume set presents a comprehensive description of laboratory animal genetics, diseases, health monitoring, nutrition, and the environmental impact on animal testing. It considers the ethics of animal experimentation through a complete review of European and North American legislation on the topic. It discusses alternatives to animal experiments, including the use of isolated organs, cell cultures, and computer simulations. The book also examines general methods, including experimental design and statistical evaluation, non-surgical and surgical techniques, anesthesia, and post-mortem examinations. Reviews of animal models for studying diseases of different organ systems, infectious diseases, cancer, and toxicology are featured as well.

Table of Contents

Animal Research and Ethics, P. Sandoe European Legislation on the Use of Live Animals for Scientific Research, S. Erichsen North American Legislation and Regulation of the Use of Live Animals for Scientific Research, M.B. Dennis, Jr. and G.L. Van Hoosier, Jr. Good Laboratory Practice, B. Lissau Classification of Animal Experiments, K.J. OEbrink Laboratory Animal Science and Service Organizations, O. Kugelberg and L. Wass Allergy to Laboratory Animals, S. Hunskaar and R.T. Fosse Zoonoses, A. Detmer Laboratory Animal Facilities, D.R. Sorensen Laboratory Animal Genetics and Genetic Monitoring, F. Dagnaes-Hansen Health Status and the Effects of Microbial Organisms on Animal Experiments, A.K. Hansen Health Monitoring, C. Rehbinder Nutrition and the Importance of Nutrients to Animal Experiments, A. Chwalibog Environmental Impact on Animal Experiments, P. Svendsen Experimental Design and Statistical Evaluation, A. Volund Common Non-Surgical Techniques and Procedures, K. Iwarsson, L. Lindberg, and T. Waller Gnotobiology, A. Hem Monoclonal and Polyclonal Antibodies, K. Erb and J. Hau Laboratory Animal Anesthesia, P. Svendsen The Treatment of Pain and Suffering in Laboratory Animals, A.J. Smith Surgical Procedures, H.P. Olesen Microsurgical Procedures in Experimental Research, D.A. Steinbruchel Postmortem Procedures, R.E. Feinstein Isolated Organs as Replacements for Vertebrate Animals, J.J. Holst Cell Cultures as Replacements for Vertebrate Animals, K.H.O. Pelkonen Computers as Alternatives to Animals in Biomedical Science, R. Fosse Index

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