書誌事項

Synthetic oligosaccharides : indispensable probes for the life sciences

Pavol Kováč, editor

(ACS symposium series, 560)

American Chemical Society, 1994

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注記

"Developed from a symposium sponsored by the Division of Carbohydrate Chemistry at the Southeast Regional Meeting of the American Chemical Society, Johnston City, Tennessee, October 17-20, 1993."

Includes bibliographical references and indexes

内容説明・目次

内容説明

Reviews the use of synthetic oligosaccharides in biochemistry, immunology, pharmaceutical and medicinal chemistry. Presents strategies for synthesis of complex oligosaccharides. Discusses the mechanisms of interaction between carbohydrates and biologically important proteins, such as enzymes, immunoglobulins, and receptor proteins. Valuable reading for biochemists, immunologists, pharmaceutical chemists, organic synthetic chemists, pharmacologists, and researchers in the life sciences.

目次

  • Synthetic Oligosaccharides in Glycobiology: An Overview
  • Drugs Based on Carbohydrates: Past and Future
  • Sugar Cyanoethylidene Derivatives: Useful Tools for the Chemical Synthesis of Oligosaccharides and Regular Polysaccharides
  • Applications of Stannyl Ethers and Stannylene Acetals to Oligosaccharide Synthesis
  • Flexibility of Biomolecules: Implications for Oligosaccharides
  • Synthetic Oligosaccharides as Probes for Investigating the Binding of Heparin to Antithrombin III
  • Synthesis and Antigenic Properties of Sialic Acid Based Dendrimers
  • Synthetic Acceptors for *a-L-Fucosyltransferases
  • Oligosaccharide-Polyacrylamide Conjugates of Immunological Interest: Synthesis and Applications
  • Synthetic Saccharides Can Delineate the Binding of Polysaccharide to Monoclonal Antibodies
  • Synthesis of Sialo-oligosaccharides and Their Ceramide Derivatives as Tools for Elucidation of Biologic Functions of Gangliosides
  • Photolabile, Spacer-Modified Oligosaccharides for Regioselective Chemical Modification and Probing of Receptor Binding Sites
  • Ganglioside Lactams as Analogs of Ganglioside Lactones
  • Stereocontrolled Approaches to O-Glycopeptide Synthesis
  • Synthetic Probe for Study of Molecules Related to Selectin Family
  • Chemical Synthesis of Sialylated Glycoconjugates

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