Antiarrhythmic therapy : a pathophysiologic approach

著者

書誌事項

Antiarrhythmic therapy : a pathophysiologic approach

by Members of the Sicilian Gambit who coauthored the volume ; Günter Breithardt ... [et al.]

Futura Pub. Co., 1994

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注記

Includes bibliographical references (p. 265-319) and index

内容説明・目次

内容説明

The goal of the Gambit is to bring to our understanding of arrhythmias and their therapy into the next century by incorporating the latest understanding of the cellular and molecular mechanisms responsible for arrhythmias and their clinical expression with the subcellular targets to which drugs bind. The approach is pathophysiologic, stressing identification of those components of the arrhythmia-provoking spectrum that are most vulnerable to therapeutic

目次

  • Section I: The Sicilian Gambit: General Introduction: The Sicilian Gambit: Overview and Intent
  • Molecular Targets for Drug Action
  • How Specific Targets Can Be Identified and Attacked
  • Electrophysiologic Mechanisms for Cardiac Arrhythmias
  • The Sicilian Gambit Approach to Antiarrhythmic Drug Actions
  • Section II: Clinical Arrhythmias: Identification of Critical Components and Vulnerable Parameters
  • Clinical Electrophysiologic Evaluation of Arrhythmias and of Antiarrhythmiac Drug Actions
  • The Concept of the Vulnerable Parameter and Its Application to Specific Arrhythmias
  • Catecholamine-Dependent Tachycardias
  • Section III: Specific Cardiac Arrhythmias: Supraventricular Tachycardias
  • Atrial Flutter and Atrial Fibrillation: Mechanisms
  • Atrial Flutter and Atrial Fibrillation: Treatment
  • Ventricular Extrasystoles: Prevention and Treatment
  • Ventricular Tachycardia
  • Ventricular Fibrillation
  • The Long QT Syndrome
  • Section IV: Where to next? Directions in Drug Development
  • The Future of Drug Development

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