Mechanisms of immunological self-tolerance

著者

    • Kroemer, Guido

書誌事項

Mechanisms of immunological self-tolerance

Guido Kroemer

(Molecular biology intelligence unit)

R.G. Landes, 1994

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注記

"Catalog no.: LN9116"--T.p. verso

Includes bibliographical references (p. [116]-169) and index

内容説明・目次

内容説明

This book reviews the multiple mechanisms that are involved in maintaining immunological self-tolerance. It presents an overall organigram of immune homeostasis, revealing the strategema of the immune system to take advantage of several tolerance-inducing mechanisms that are interconnected in series. The molecular mechanisms governing each individual tolerance-inducing event are explored extensively. Topics discussed include: clonal deletion of self-reactive T and B cells, with regard to recent progress in apoptosis regulation; different types of functional activation of lymphocytes dealt with from a molecular point of view; and non-specific immnosuppression by cytokines and hormones, as well as the arguments in favour of a network control of immune function.

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