Alzheimer's disease : optimizing drug development strategies

著者

• Cutler, Neal R.
• Sramek, John J.
• Veroff, Amy E.

書誌事項

Alzheimer's disease : optimizing drug development strategies

Neal R. Cutler, John J. Sramek, Amy E. Veroff

Wiley, c1994

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Examining improved drug development strategies in Alzheimer's disease, this study highlights the importance of designing clinical trial protocols that ensure an adequate assessment of the efficacy and safety of potential pharmacological treatments.

目次

• ALZHEIMER'S DISEASE: The Problem and the Search for Solutions
• Diagnosis
• Procedures and Criteria
• Basic and Clinical Alzheimer's Disease Models
• End Organ Responses
• Mechanisms of Action and Measures of Efficacy
• Central
• Structural and Functional Measures
• Peripheral: Red Blood Cell Cholinesterase and Salivary Amylase
• Neuropsychological: the Computerized Neuropsychological Test Battery
• CLINICAL TRIALS: Enhancing and Accelerating the Drug Development Process: Subject Selection and Sample Size
• Age as a Factor in Drug Development
• Finding the Dose: the Bridging Study.

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA24025702
• ISBN:
  • 0471951455
• LCCN: 94010062
• 出版国コード: uk
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Chichester ; New York
• ページ数/冊数: viii, 168 p.
• 大きさ: 24 cm
• 分類:
  • LCC : RC523
  • NLM : WM 220 C989a 1994
  • DC20 : 616.8/31061
• 件名:
  • LCSH : Alzheimer's disease -- Chemotherapy -- Evaluation
  • LCSH : Drugs -- Testing
  • LCSH : Clinical trials
  • MESH : Alzheimer's Disease -- drug therapy
  • MESH : Clinical Trials
  • MESH : Drug Evaluation