Fundamentals of preparative and nonlinear chromatography

Bibliographic Information

Fundamentals of preparative and nonlinear chromatography

Georges Guiochon, Sadroddin Golshan Shirazi, Anita M. Katti

Academic Press, c1994

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Includes bibliographical references and index

Description and Table of Contents

Description

Non-linear chromatography has become an important separation technique for preparitive and process-scale chromatographic applications in industry. This text provides a consolidated summary of the parameters necessary to the optimization of preparative chromotography, with detailed information on the design, economics and critical parameters of preparative separations. The illustrations turn difficult mathematics into easily understood pictures. The concepts outlined are illustrated through numerous examples.

Table of Contents

Introduction, Definitions, Goal. The Mass Balance Equation of Chromatography and Its Properties. Single-Component Equilibrium Isotherms. Competitive Equilibrium Isotherms. Fundamentals of Transfer Phenomena Involved in Chromatography. Linear Chromatography. The Ideal Model of Chromatography: Elution of Single Component Bands. The Ideal Model of Chromatography: Elution of Two-Component Bands. The Ideal Model of Chromatography: Displacement Chromatography. The Equilibrium-Dispersive Model: Elution of Single-Component Bands. The Equilibrium-Dispersive Model: Isocratic Separations of Two-Component Bands and Gradient Elution. The Equilibrium-Dispersive Model: Frontal Analysis and Displacement. The Equilibrium-Dispersive Model: System Peaks in Chromatography. The Kinetic Models: Frontal Analysis and Elution of Single Component Bands. The Kinetic Models: Frontal Analysis, Elution and Displacement of Multicomponent Bands. Optimization of the Experimental Condition in Preparative Chromatography.

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