Immunological and molecular aspects of bacterial virulence
著者
書誌事項
Immunological and molecular aspects of bacterial virulence
J. Wiley & Sons, 1995
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The living mammalian host provides a unique environment for bacterial colonisation. It is not only subject to passive change but has evolved highly specialised mechanisms, together constituting the immune system, to actively discourage microbial colonisation. It brings together under one cover aspects of the human immune response to bacteria and the genetic systems of pathogenic bacteria as well as details of the bacterial molecules involved in virulence. Although biased towards pathogenic bacteria of humans, the principles covered are equally applicable to veterinary pathogens. Immunological and Molecular Aspects of Bacterial Virulence caters for undergraduate and postgraduate science students of human and veterinary bacteriology who wish to gain a better understanding of the fundamental aspects of bacterial virulence.
目次
Pathogenic Bacteria in Context: An Overview. HOST DEFENCE: THE IMMUNE SYSTEM. Non-Clonal Recognition and Immunomodulation. Clonal Recognition: Antibodies and T-Cell Receptors. Clearance Mechanisms: Complement, Phagocytosis and Cell Mediated Cytotoxicity. THE BACTERIAL INVASION. Bacterial Nutrition: The Host as a Substrate. Bacterial Exotoxins Which Act Inside Host Cells. Bacterial Surface Molecules and Virulence. Intracellular Invasion, Survival and Growth. Genetic Variation and Regulation of Virulence Determinants. Appendix. Index.
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