Biochemistry of redox reactions
著者
書誌事項
Biochemistry of redox reactions
(The metabolism of drugs and other xenobiotics)
Academic Press, c1995
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Surpassing the 1976 book by Testa and Jenner, Drug Metabolism: Chemical and Biochemical Aspects (Dekker), this informative, up-to-date text includes the following features, unavailable elsewhere: First in a set of books to provide a comprehensive coverage of drug metabolism; Opening chapter provides a general introduction to the complete set of books; Other chapters cover reaction mechanisms, catalytic cycles, regio- and stereoselectivities, types of substrates, reactivity of intermediates, and drug-enzyme interactions; Extensive detailed diagrams of reaction pathways and chemical structures
目次
Xenobiotic Metabolism: The Global View.
Xenobiotic Metabolism: The Biochemical View.
Dehydrogenation of Alcohols and Aldehydes, Carbonyl Reduction.
The Nature and Functioning of Cytochromes P450 and Flavin-Containing-Monooxygenases.
Carbon Oxidations Catalyzed by Cytochromes P450.
Monooxygenase-Catalyzed N-C Cleavage.
Monooxygenase-Catalyzed Oxidation of Oxygen- and Sulfur-Containing Compounds.
Oxidative Dehalogenation and Dealkylation of Organometallics.
Oxidations Catalyzed by Various Oxidases and Monooxygenases.
Reactions Catalyzed by Peroxidases.
Oxidation of Mercury, Silicon, Phosphorus, Arsenic, Selenium, and Halogens.
Reductions Catalyzed by Cytochrome P450 and Other Oxidoreductases.
Various Enzymatic and Nonenzymatic Reactions.
Conclusion and Outlook.
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