Alzheimer's disease : clinical and treatment perspectives
著者
書誌事項
Alzheimer's disease : clinical and treatment perspectives
J. Wiley & Sons, c1995
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Progress in the basic and clinical research of Alzheimer's disease has been substantial in recent years and has contributed significantly to our understanding of the pathology which underlies the disease process. Although there has been no treatment breakthrough, advances in neuroscience research have provided a clearer focus for the clinical development of promising therapeutic strategies. Presented here is a comprehensive and authoritative account of the latest discoveries on Alzheimer's disease. Crucial areas of basic research are discussed as well as viable neurotransmitter treatment approaches and a method for determining the proper dose to use in clinical drug trials. Written by an international group of authors, the book will be of value to all researchers in Alzheimer's disease and to neuroscientists, neurologists and psychiatrists.
目次
The Diagnosis of Alzheimer's Disease (C. Gottfries, et al.). Biochemical Aspects and CSF Markers in Alzheimer's Disease (K. Blennow, et al.). Brain Imaging and Alzheimer's Disease (Ph. Scheltens). The Cholinergic Hypothesis in Alzheimer's DiseaseClinical Evidence Gained with Velnacrine (K. Siegfried). Gangliosides Selectively Diminished in Early-Onset Alzheimer's Disease (AD Type 1) Suggest Synapse Loss as Primary Event (L. Svennerholm, et al.). Alzheimer's Disease: Is the Improvement of Cholinergic Transmission the Correct Strategy? (D. Bowen, et al.). -Amyloid, Cytokines and Other Potential Strategies for Modifying Pathophysiology of Alzheimer's Disease (C. Wilmot, et al.). Multiple Neurotransmitter Strategies for Treatment of Alzheimer's Disease (F. Huff). The Use of Bridging Studies in Drug Development for Alzheimer's Disease Therapeutics (N. Cutler, et al.). Index.
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