Myocardial failure
著者
書誌事項
Myocardial failure
(International Boehringer Mannheim symposia)
Springer-Verlag, 1977
- :Berlin
- :New York
大学図書館所蔵 全10件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
"International symposium, Rottach-Egern/Tegernsee, Germany, June 17-19, 1976, under the auspices of the European Society of Cardiology."
Includes bibliographies and index
内容説明・目次
内容説明
More than 10 years have passed since the memorable symposium on "Myocardial Contractility," edited by R. D. Tanz, F. Kavaler and J. Roberts (New York and London, Academic Press, 1967). PathogeneSis of myocardial failure still involves many questions. The latest scien tific findings on fundamentals of myocardial contraction encouraged us to organize this international symposium held in Rottach-Egern at Tegernsee (Germany), June 17 to 19, 1976 sponsored by the European Society of Cardio~ogy. It seemed appropriate to assemble prominent workers in this field in an attempt to correlate their respective in formation on cardiac function. In this connection it must be remembered that our present understand ing of the cardiovascular system and today's therapeutic and preventive measures are the fruits of yesterday's research. Further progress in this field will be conditioned by various circumstances: to win highly motivated creative people for clinical research, to mediate time and contacts for their learning new methods, and to provide adequate faci lities for scientific work in our hospitals. Therefore, the aim of the conference was to discuss those aspects of myocardial failure, that are believed to require further studies in the future by integrated efforts of research workers in several disciplines, especially to promote the pertinent exchange of ideas between basic and clinical research.
目次
Session I. Molecular Basis of Myocardial Function.- 1. Regulatory and Contractile Proteins.- Introductory Remarks.- The Structural Basis of Contraction in Muscle and Its Study by Rapid X-Ray Diffraction Methods.- The Myosin Cross-Bridge as Revealed by Structure Studies.- Myosin-Linked Regulation: A Chemical Approach.- Myocardial Cross-Bridge Activity and Its Regulation by Ca++, Phosphate and Stretch.- Myosin Characteristics and Immunological Properties of Myocardial Tissue.- Concluding Remarks.- 2. Sarcoplasmatic Reticulum.- Introductory Remarks.- Relation of Calcium Permeability to the Ca++ Concentration Gradient Across the Sarcoplasmic Reticulum.- Calcium Binding and Cardiac Myofibril Activation.- Cyclic Nucleotides and Cardiac Contractility.- 3. Membrane-Bound Receptors.- Introductory Remarks.- Biochemical Characteristics of the Sodium Pump: Indications for a Half-of-Sites Reactivity of (Na+ + K+)-ATPase.- Receptor for Cardiac Glycosides.- Adenylate Cyclase Regulation and ?-Adrenergic Receptors in Guinea-Pig Myocardial Tissue.- The Role of the Mitochondrial Adenine Nucleotide Transport in Heart.- Session II. Clinical Aspects of Myocardial Failure.- 1. New Diagnostic Procedures.- Introductory Remarks.- Myocardial Biopsy Techniques.- Cellular and Subcellular Morphology of Biopsy Material.- Ultrastructure of Degenerated Muscle Cells in Patients With Cardiac Hypertrophy.- Humoral and Cellular Studies in Diseases With Heart-Reactive Antibodies.- Relationship Between Pulmonary Artery Pressure and Echocardiographic Mitral Valve Closure in Patients With Acute Myocardial Infarction.- Echocardiographic Evaluation of Myocardial Performance During Infusion of Angiotensin and Handgrip-Exercise.- 2. Problems of Etiology and Classification.- Introductory Remarks.- Classification and Natural History of Primary Cardiomyopathies.- Myocardial Lesions in Cardiomyopathies.- Cardiomyopathies Related to Immunological Processes.- Metabolic Heart Disease With Special Reference to Carbohydrate Metabolism in Health and Disease.- Session III. Clinical Pharmacology.- 1. Usefulness of Cardioactive Agents.- Introductory Remarks.- Contraction and Relaxation of Heart Muscle as Influenced by cAMP, Isoproterenol, Glucagon, Ouabain, and Calcium.- Direct Effects of Diuretic Drugs on the Myocardium.- Circulatory and Contractile Effects of Thyroid Hormones.- 2. Drugs Influencing Myocardial Contractility.- Introductory Remarks.- On the Inotropic and Arrhythmogenic Effects of Digitalis.- Beta-Blockers in Myocardial Failure.- The Hemodynamic Effects of Antiarrhythmic Drugs on the Depressed Myocardium.
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