Ovarian follicular and corpus luteum function

書誌事項

Ovarian follicular and corpus luteum function

edited by Cornelia P. Channing and John M. Marsh, and William A. Sadler

(Advances in experimental medicine and biology, v. 112)

Plenum Press, c1979

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注記

"Proceedings of the second workshop ... sponsored by the Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland."

Includes bibliographical references and index

内容説明・目次

目次

Section I.- Introductory Remarks: Ruminations on Ovarian Function.- Section II.- Follicular Growth in the Rat: A Reevaluation of the Roles of FSH and LH.- LH-Induced Desensitization of the Adenylyl Cyclase System in Ovarian Follicles.- Gonadal LH receptors: Resolution from Adenylate Cyclase and Transfer to Heterologous Cells.- Prolactin Control of Receptor for Estradiol in Corpora Lutea of Pregnant Rats.- Chairperson's Remarks.- Lateral Mobility and Internalization of Hormone Receptors to Human Chorionic Gonadotropin in Cultured Rat Granulosa Cells.- FSH Stimulation of Mucopolysaccharide Synthesis in Rat and Porcine Ovary.- Immunologic Impairment of ?5-3B Hydroxysteroid Dehydrogenase and Its Effect on Ovarian Function: The Use of a Purified Enzyme.- Receptors for Gonadotrophins in the Ovine Follicle During Growth and Atresia.- Effect of Oestradiol-17? and Gonadotrophins on Prostaglandin Production by Pre-Ovulatory Pig Follicles Superfused in vitro.- LH-Stimulated cAMP Formation in Rat Granulosa Cells During Follicular Maturation - a Non-Refractory Response.- Effect of the Administration of an Ovulatory Dose of HCG on the Subcellular Distribution of Follicular Protein Kinase.- Structural Analysis of Granulosa Cells from Human Ovaries in Correlation with Function.- Regulation of LH(hCG)-Receptor and Adenylate Cyclase in Luteinizing Granulosa Cells.- Changes in Responsiveness of Porcine Granulosa Cells to Prostaglandins and Luteinizing Hormone in Terms of Cyclic-AMP Accumulation During Follicular Maturation.- Some Morphological and Functional Characteristics of Cells of the Porcine Theca Interna in Tissue Culture.- The Control of Ovulation in the Cow by Prostaglandin Inhibitor.- Section III.- Steroidal Modulation of Steroid Secretion in vitro: An Experimental Approach to Intra-Follicular Regulatory Mechanisms.- On the Mechanism of Prolactin Stimulation of Steroidogenesis.- Steroid Secretion by Perifused Ovarian Follicles of Immature, PMSG-Treated Immature, and Mature Rabbits.- Effects of Follicular Development on the Ability of Cultured Porcine Granulosa Cells to Convert Androgens to Estrogens.- Testosterone Synthesis by Chicken Follicular Cells.- Modulation of Thecal Progesterone Secretion by Estradiol-17?.- Chairperson's Remarks.- Steroid Secretion by Ovarian Follicles of Rabbits in Different Reproductive States.- Hormone Requirements for Long-Term Maintenance of Rat Granulosa Cell Cultures.- Long-Term Perfusion of Rabbit Ovarian Follicles.- Estrogen Inhibits Porcine Thecal Androgen Production in vitro.- Antral Follicular and Interstitial Contributions to Progesterone Secretion in the Proestrous Hamster.- Section IV.- Meiotic Maturation of Mouse Oocytes in vitro.- Mammalian Oocyte Maturation: Model Systems and Their Physiological Relevance.- Action of Porcine Follicular Fluid Oocyte Maturation Inhibitor in vitro: Possible Role of the Cumulus Cells.- Relationship Between Steroidogenesis and Oocyte Maturation in Rat Graafian Follicles Cultured in vitro.- Chairperson's Remarks.- The Somatic-Germ Cell Complex.- Rapid Oocyte Death Prior to and at Puberty in Neonatally Thymectomized Mice.- Maturation and Atresia of Human Oocytes in vivo.- Section V.- Follicular Non-Steroidal Regulators.- The Influence of Follicular Fluid on Progesterone Secretion by Porcine Granulosa Cells in vitro.- Inhibition of in vivo and in vitro FSH Secretion by Steroid-Free Hamster Ovarian Extracts.- The Differential Ability of Porcine Follicular Fluid to Suppress Serum FSH in Female Rats from 6 Days of Age to Adulthood.- Evidence for the Presence of a Low Molecular Weight Follitropin Binding Inhibitor in Bovine Follicular Fluid.- Chairperson's Remarks.- Inhibition by Follicular Fluid of Luteinizing Hormone-Sensitive Adenylate Cyclase in Ovarian Plasma Membranes.- Inhibitory Effect of Charcoal-Treated Porcine Follicular Fluid upon Serum FSH Levels and Follicular Development in the Rhesus Monkey.- Follicular Fluid Inhibition of Ovulation.- Modulation of Pituitary Responsiveness to LHRH by Porcine Follicular Fluid: Time and Dose-Dependent Effects.- Isolation and Preliminary Characterization of Inhibin-f.- Evidence that the Pituitary Gland is the Site of Inhibitory Action of Porcine Follicular Fluid upon FSH Secretion in the Rat.- Section VI.- Estrogen Action in the Corpus Luteum.- Follicular Determinants of Corpus Luteum Function in the Human Ovary.- LH Receptors in the Ovine Corpus Luteum During the Estrous Cycle and Early Pregnancy.- Gonadotropin Action in Isolated Ovarian Luteal Cells: The Intermediate Role of Adenosine 3?, 5? Cyclic Monophosphate in Hormonal Stimulation of Progesterone Synthesis.- Chairperson's Remarks.- Changes in Ovarian Mitochondria: Early Indicators of Follicular Luteinization.- Prostaglandin F2? and Progesterone Synthesis in vitro by Bovine Corpora Lutea of Early Pregnancy.- Luteal Phase Deficiencies in Peripubertal Rhesus Monkeys: Mechanistic Considerations.- Cellular Mechanisms Involved in Luteolysis.- Role of Pituitary LH and Placenta in Luteal Progesterone Production and Maintenance of Pregnancy in the Rat.- Relationships Between Cholesterol Supply and Luteal Mitochondrial Steroid Synthesis.- A Comparison of the LH Control of Progesterone Synthesis in Small and Large Cells from Pregnant Cow Corpus Luteum.- Cytochalasin B Inhibition of Luteinizing Hormone Action on Bovine Luteal Cells.- Section VII.- Mechanisms of PGF2? Action in Functional Luteolysis.- Prostaglandin F2? and Its 13-Dehydro Analogs: Comparative Luteolytic Effects in vivo.- Effects of Cholera Toxin, LH, and PGF2? on Steroidogenesis in Luteal Cells.- Effects of Prostaglandin F2?, Estradiol and Luteinizing Hormone in Dispersed Cell Preparations of Bovine Corpora Lutea.- Chairperson's Remarks.- In vitro Release of Progesterone and Prostaglandins F and E by Porcine Luteal and Endometrial Tissue During Induced Luteolysis.- Demonstration of Luteal Cell Membrane Receptors for Prostaglandin F2? by Ultrastructural and Binding Analysis.- Prostaglandin F2? and Progesterone Release in vitro by Ovine Luteal Tissue During Induced Luteolysis.- Section VIII.- Luteal Desensitization: Hormonal Regulation of LH Receptors, Adenylate Cyclase, and Steroidogenic Responses in the Luteal Cell.- Interactions Among Estrogen, Prolactin, and Luteinizing Hormone at the Level of Adenylyl Cyclase in the Corpus Luteum: Findings and Physiological Correlates.- Desensitization and Recovery of PGE2-responsive Ovarian Adenylate Cyclase Modulated by Agents Affecting Cytoskeletal Function.- Inhibitory Effects of Treatment with LHRH or Its Agonists on Ovarian Receptor Levels and Function.- Chairperson's Remarks.- Concluding Remarks.- Lutropin Induced Desensitization of Rat Ovarian Adenylate Cyclase: A GTP-Dependent Process.- hCG-Induced Loss of LH-hCG Receptor and Desensitization of Adenylate Cyclase.- Evidence of a Greater Activity of LH/HCG Binding Inhibitor Present in Aqueous Extracts from Old Compared to Young Porcine Corpus Luteum.- Suppression of Ovarian Function by LHRH and Its Analogues in Pregnant Rats.- Section IX.- Clinical Applications in the Area of Contraceptive Development.- Serum Immunoreactive Relaxin Concentrations in Human Pregnancy, Labor, and the Puerperium.- Effect of Removal of Carbohydrate Residues upon the Half Life and in vivo Biological Activity of Human Chorionic Gonadotropin.- A Procedure for Evaluating Luteolytic Agents in Primates.- Summing Up.- Participants.

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