Handbook of pharmacokinetic/pharmacodynamic correlation

書誌事項

Handbook of pharmacokinetic/pharmacodynamic correlation

edited by Harmut Derendorf, Günter Hochhaus

(Handbooks of pharmacology and toxicology / series editor Mannfred A. Hollinger)

CRC Press, c1995

タイトル別名

Handbook pharmacokinetic/pharmacodynamic crrelation

大学図書館所蔵 件 / 15

この図書・雑誌をさがす

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and time, and pharmacodynamics (PD), the relationship between drug effects and concentration, this handbook examines the relevant relationship between drug effects and time. It provides a systematic overview of how PK is linked to PD, introduces the basic concepts of PK-PD modeling and presents the underlying theory behind it, and discusses the specific aspects of PK-PD modeling for various classes of drugs.

目次

Pharmacokinetic-Pharmacodynamic Modeling of Reversible Drug Effects, J. Venitz. Pharmacokinetic-Pharmacodynamic Modeling of Irreversible Drug Effects, S. Ebert. Pharmacokinetic-Pharmacodynamic Modeling in Drug Development: Comments and Applications, J. Fleishaker and J. Ferry. Dose Optimization Based on Pharmacokinetic-Pharmacodynamic Modeling, G. Hochhaus and H. Derendorf. Pharmacokinetic-Pharmacodynamic Correlations of Anesthetics, V.D. Schmith and K. Muir. Pharmacokinetic-Pharmacodynamic Correlations of Analgesics, J.S. Walker. Pharmacokinetic-Pharmacodynamic Correlations of Benzodiazepines, S.K. Gupta. Pharmacokinetic-Pharmacodynamic Correlations of Anticonvulsants, M. Danhof and R. Voskuyl. Pharmacokinetic-Pharmacodynamic Correlations of Cardiovascular Drugs, R. Lalonde. Pharmacokinetic-Pharmacodynamic Correlations of Selected Vasodilators, T.-B. Tzeng and H.-L. Fung. Pharmacokinetic-Pharmacodynamic Correlations of Anticoagulants, D. Mungall and R.H. White. Pharmacokinetic-Pharmacodynamic Correlations of Antihistamines, E. Snoeck, A. Van Peer, and J. Heykants. B2-Agonists: Terbutaline, Albuterol, and Fenoterol, G. Hochhaus and H. Moellmann. Pharmacokinetic-Pharmacodynamic Correlations of Corticosteriods, H. Moellmann, S. Balbach, G. Hochhaus, J. Barth, and H. Derendorf. Pharmacokinetic-Pharmacodynamic Modeling of Antibiotics, A. Nolting and H. Derendorf. Clinical Pharmacodynamics of Anticancer Drugs, H.L. McLeod and W.E. Evans. Computer Applications in Clinical Pharmacokinetics and Pharmacodynamics, D. Mungall, J. Heissler, and M. Kaltenbach.

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