G protein-coupled receptors
著者
書誌事項
G protein-coupled receptors
（Molecular biology intelligence unit）
R.G. Landes , Tokyo ; Springer-Verlag, c1995
- :U.S. and Canada
- :international
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注記
Includes bibliographical references and index
内容説明・目次
- 巻冊次
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:U.S. and Canada ISBN 9781570590580
内容説明
This text considers the molecular basis of cell function G protein-coupled receptors. These are all an essential part of the signalling pathway that allows cells to communicate with one another, and it is on such pathways that all life processes depend. This text focuses on recent advances in the structural and functional characterization of receptors that influence intracellular signalling through interaction with intracellular GTP binding proteins (G proteins). Molecular cloning of members of the G protein-coupled receptor superfamily has complemented pharmacological investigations by providing an awareness of the structural and functional diversity of these receptors. The text describes molecular variants representing distinct receptors subtypes and discrete functional properties. It aims to increase understanding of the involvement of particular receptor subtypes in normal and pathophysiological processes.
- 巻冊次
-
:international ISBN 9783540588870
内容説明
This book is about the recent advances in the structural and functional characterization of receptors that influence intracellular signalling events through interaction with intracellular GTP-binding proteins (G proteins). Molecular cloning of members of the G protein-coupled receptor superfamily has complemented pharmacological investigations in providing a realization of the structural and functional diversity of these receptors. An increased understanding of the involvement of particular receptor subtypes in normal and pathophysiological processes represents exciting possibilities for the development of highly specific and effective therapeutic agents.
目次
1. Cell Surface Receptors and the G Protein-Coupled Receptor Superfamily.- 2. Signaling Through G Protein-Coupled Receptors.- 3. Structural Determinants of Receptor Function.- 4. G Protein-Coupled Receptors, Pathology and Therapeutic Strategies.- 5. Future Prospects.
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