Viroceptors, virokines and related immune modulators encoded by DNA viruses
著者
書誌事項
Viroceptors, virokines and related immune modulators encoded by DNA viruses
(Molecular biology intelligence unit)
R.G. Landes , Springer-Verlag, c1995
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This study describes how proteins encoded by the larger DNA viruses (such as poxviruses, herpesviruses and adenoviruses) interact with elements of the vertebrate immune system to favour propagation in infected hosts. All mammalian viruses in the wild have adapted to the selection pressure exerted by the various effector arms of the immune apparatus, but the DNA viruses with larger genomes have the luxury of being able to encode and express specific viral proteins whose function is to directly subvert or modulate immune recognition and clearance. Up-to-date information is provided of how such viral immune regulator proteins have co-evolved with the host proteins that mediate natural and acquired immunity.
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