Molecular biology of collagen matrix in the heart
Author(s)
Bibliographic Information
Molecular biology of collagen matrix in the heart
（Molecular biology intelligence unit）
R.G. Landes , Springer-Verlag, 1995
- : U.S.
- : Int.
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Description and Table of Contents
- Volume
-
: U.S. ISBN 9781570590702
Description
This work explores the molecular and cellular biology of the collagen matrix of the heart. Collagen is the major protein of the extracellular matrix. The extracellular matrix of the heart is an intricate network, with its importance becoming apparent to the developmental and functional integrity of the mycardium. The book provides a comprehensive introduction to the collagen matrix in general, including information on collagen types and their tissue specificity. It then discusses different aspects of the molecular and cellular biology of the collagen matrix, the impact of growth factors on the expression of the mycardial collagen matrix, and myocardial collagen gene regulation under pathophysiological conditions.
- Volume
-
: Int. ISBN 9783540588979
Description
This is a survey of the molecular and cellular biology of the collagen matrix of the heart. It is now recognized that the remodelling of the fibrillar collagen matrix that occurs under various pathophysiological conditions may adversely alter myocardial stiffness and ultimately lead to heart failure. The book begins with a comprehensive introductory chapter on the collagen matrix in general, including information on collagen types and their tissue specificity. It then focuses on different aspects of the molecular and cellular biology of the collagen matrix in the heart, the impact of growth factors on the expression of the myocardial collagen matrix, and myocardial collagen gene regulation under pathophysiological conditions.
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