Pacemaker activity and intercellular communication

著者

書誌事項

Pacemaker activity and intercellular communication

edited by Jan D. Huizinga

CRC Press, c1995

大学図書館所蔵 件 / 全3件

この図書・雑誌をさがす

注記

Includes bibliographical references and index

内容説明・目次

内容説明

The book focuses on enhancing our understanding of pacemaker systems and associated mechanisms of intercellular communication. Three different physiological systems are compared: the cadiac system, the ??cells of the pancreas, and the gastrointestinal tract. Experts in all three areas highlight the parallels and comparisons among the systems. Emphasis is placed on finding precise characteristics of all cell types involved in pacemaker activity. The interpretation of data on single isolated cells in light of tissue function receives thorough discussion. Ion channel characteristics involved in the generation of action potential and pacemaker components are described in detail. A fascinating but largely unexplored area is touched upon: the electrical and metabolic coupling of different cell types. A most valuable feature is that most investigators have explored a variety of techniques to examine cell function: patch clamp studies, intracellular voltage recording, intracellular calcium measurements, gap junction conductance measurements, dye spread techniques, and more. Various aspects of the molecular biology of gap junction and ion channels are explored.

目次

Introduction Pacemaker Activity and Intercellular Communication: An Introduction to the Book, J.D. Huizinga The Heart Generation of Pacemaker Activity in Mammalian Sinoatrial Node, W.R. Giles The Sinoatrial Node: Structure, Inhomogeneity, and Intercellular Interaction, L.N. Bouman and H.J. Jongsma Electrophysiology of Gap Junctional Conductance, M. Chanson and D.C. Spray Propagation of Pacemaker Activity: Interaction between Pacemaker Cells and Atrial Tissue, D. Noble, H.F. Brown, and R.L. Winslow Structural Patterns of Muscle and Innervation in the Sinoatrial Node, L.A. Roberts Pacemaker Currents and Their Neural Modulation, A. Zaza, M. Mangoni, and D. DiFrancesco Pacemaker Activity in Explanted Cardiac Cells, O.F. Schanne, R. Dumaine, and E. Ruiz Petrich Gastrointestinal Smooth Muscle Pacemaker Activity and Intercellular Communication in the Gastrointestin Musculature, L.W.C. Liu, N. Sperelakis, and J.D. Huizinga Generation and Propagation of Rhythmicity in Gastrointestinal Smooth Muscle, N.G. Publicover Structural Aspects of Interstitial Cells of Cajal as Intestinal Pacemaker Cells, L. Thuneberg, J.J. Rumessen, H.B. Mikkelsen, S. Peters, and H. Jessen Ion Channels Involved in Gastrointestinal Action Potential Generation., A. Molleman, S. Sims, J.C.F. Lee, and J.D. Huizinga Spontaneous Electrical Activity and Slow-Wave Origin in the Stomach and Small Intestine, A.J. Bauer, and B. Ermentrout ??Cells of the Pancreas Generation and Control of Bursting Electrical Activity in Pancreatic ??Cells, D.L. Cook and W.F. Hopkins Junctional Coupling of Pancreatic ?-Cells, P. Meda Multicellular Synchronous Calcium Oscillations in Pancreatic Islets of Langerhans, A. Nada, B. Soria, and M. Valdeolmillos Mechanisms for Fast Intercellular Communication within a Single Islet of Langerhans, E.M Perez-Armendariz, I. Atwater, and M.V.L. Bennett Theoretical Aspects of Synchronized Bursting in ?-Cells, A. Sherman

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